Westphall places a new doctor in charge of the E.R., and she immediately clashes with Fiscus; Axelrod's visit to Mrs. Hufnagel's apartment sends her back to the hospital; Rosenthal and Clarendon reconcile; Dr. Craig celebrates his 30th wedding anniversary with a visit from his estranged brother; Dr. Caldwell begins treatment of a disfigured girl suffering from a massive facial fibromatosis; and a junkie admits his very pregnant, 14-year-old girl friend.

Dr. Craig arranges to take Yvonne home to her parents; Ehrlich advises a plastic surgery patient behind Dr.Caldwell's back; Capt. Neal arrives to evaluate the astronaut's condition and to supervise his transfer to Walter Reed, despite Westphall and Morrison's objections; Chandler and Dr. Turner plan a vacation together; and John Doe #6 decides he's Mary Richards and plans a party to celebrate.

Mandatory drug testing causes a deep division of opinion; Morrison is haunted by his day at the prison; Axelrod is assigned to guide a 14-year-old medical student around; Griffin gets a warning from Dr. Westphall about hurting Lizzie; and Dr. Craig tries to perform magic tricks for some young patients and his housekeeper.