When Traci and Andy are sent out on an undercover training exercise, they stumble upon a young woman who is about to die of an overdose. Meanwhile, Dov finds himself on a “ride-along” with a drug dealer and old friend of his deceased brother. Back at the station, Chris and Gail deal with a teenage boy they found tied up at a graveyard; sifting through the wreckage of their relationship, to try to get to the bottom of a bullying situation.

Andy and Nick investigate when a neighborhood drug lord threatens a priest's life; a young drug-runner's refusal to turn informant leads Traci to make a decision about her career; Chris and Swarek butt heads; Dov's relationship takes a dark turn.

With the 15 Division restructuring looming, Andy and Sam’s wedding comes just in time for the gang to celebrate one last hurrah. But when Andy is taken off-course by a hitchhiker and then stranded on the side of a dead-end road with a dying man, she finds herself with no way to get help – or let Sam know she hasn’t bailed. Will she save the man’s life? Will she make it to her wedding?