Addison and Sam form a hostile takeover in order to bring the practice out of bankruptcy, as all of the doctors look for additional clients and new income streams, while Violet's friendship with Cooper is on the brink of extinction and a married couple fight for an unethical fertility treatment at Oceanside Wellness.

Addison sends a pregnant woman to St. Ambrose for help from Noah after she experiences heart complications. Meanwhile, Sam begins to rethink his friendship with Naomi; Pete and Lisa's relationship becomes increasingly complex; and Sheldon takes a stand.

While Addison deals with the unwelcome arrival of her father, Cooper is arrested because he refused to cooperate in a case involving a longtime patient. Meanwhile, Pete will stop at nothing to keep a terminally ill patient alive for as long as it takes for him to meet his new daughter.

When Addison's patient and the life of the three unborn babies she is carrying as a surrogate hang in the balance, Sam's new girlfriend, Vanessa, and Addison are sharply divided on the course of treatment. Meanwhile Cooper seeks Sheldon's help with a young patient, but their personal quarrels over Charlotte get in the way, and Naomi has a dilemma of her own between William and an unexpectedly charming Dr. Fife.