After a teen collapses while playing violin in a concert and it's discovered that she has a tumor. Dr. Hanson want to operate on the young girl's brain but the girl's mother isn't sure that is best since she recently suffered a loss of another daughter during an operation. Meanwhile, Hanson's protégé, Dr. Jonathan Seger arrives.

A soldier who was wounded in Iraq by shrapnel to his head suffers a stroke, which leads to paralysis in his left arm. Even worse, the man believes the arm doesn't belong to him but rather to a fellow soldier who died. Also, a woman is diagnosed with a so-called joking disease caused by a tumor that makes her lose memory and find most things humorous.