When a journalist disappears while working on an exposé about an innocent man serving time for murder, Danny and Baez hope that reexamining the original case will help find her. Frank reluctantly speaks out against an initiative led by Erin's office to consider drug abuse as a disease first, and a crime second.

After Anthony is shot while interviewing a witness for an upcoming murder trial, Erin enlists Anthony's archenemy, Danny, to find out who was responsible. Jamie and Eddie get in the middle of a standoff between a police lieutenant and a developmentally disabled man posing as an officer. Nicky prepares to take the police exam.