When a woman is found murdered in the hotel suite occupied by three married men, Five-0 must help the friends get over their massive hangover and retrace their steps from a wild night to find the killer. Also, Jerry witnesses a woman’s kidnapping on the streets of O’ahu.

Five-0 must go up against an aggressive U.S. marshall, Lincoln, when a man wanted for murder escapes capture and seeks asylum in the sovereign land belonging to the Nation of Hawaii.