With his enemies advancing and his troops deserting Juan's command, Rodrigo has to take a tough decision that puts Cesare's life at stake.

Rodrigo has his back on the wall as the French troops occupy the Eternal city, but thanks to his son Cesare, a fragile peace can be negotiated.

By the intervention of Spain, France is forced to withdraw, but Isabella of Spain demands a purge of the Jews from the Eternal City.

To prove himself worthy of the crown of Naples, Juan proposes to convert the Jews in a mass christening, but accidentally reveals a dark secret.

Cesare leads an investigative commission into Juan's death, but cannot find the guilty party and soon fears he himself killed his brother.