Robbie is entrusted with a device containing a baby universe; trouble brews when Scott Stotz accidentally downloads it into his head and Professor Evil Brainhead comes looking for it!

With Team Quantum's help, Olga leaves her job to open her own place on the moon, unaware of the fact that it lies on top of a test site for Professor Evil Brainhead's new destroyer ship and Robbie's kidnapped friends.

At a ceremony honoring Ray's father's heroic deeds, Professor Brainhead and Mother use a device on Ray Jr. and Ray Sr. that steals their courage.

Professor Evil Brainhead and Mother team up with Contessa De Worm to mass produce and sell Brainhead's new invention: a pen that allows the user to see the future.

Contessa de Worm traps Team Quantum in a virtual reality prison.

Professor Evil Brainhead is captured by Team Quantum, who then leave him with Olga on Earth as they hunt for Mother and her new henchmen: Commander Fuzzy and Science Officer Squeaky.

Professor Evil Brainhead switches the minds of Ray and Robbie. Now Ray is a teenage human and Robbie is a nine-dimensional man, and neither knows how to control their new bodies.

When the squirrels get their furry little paws on a shrink-ray, they decide it's time to make everyone on Earth smaller than they are so that they can "rule over the Smooth Ones forever".