Continuing where the battle left off, Teresa of the Faint Smile will now have to face the Numbers 2-5 Claymores, who have released their full power. Knowing that she has never need to release her power, how will Teresa fair against these tough opponents? Overcome by her emotions, Priscilla surpasses the limit and becomes what is known by an "Awakened One".

Having just heard the news of what happened in the City of Pieta, Isley has ordered his entire army of 27 Awakened beings to annihilate the Claymores located there. With the probability of this mission ending in success zero, no matter the odds the teams of Claymores are still determined to carve out their path of survival. Meanwhile Raki is heading towards Pieta with Isley and Priscilla when he later discovers something shocking.