He’s been dead for more than 5,000 years and poked, prodded, and probed by scientists for the last 20. Yet Ötzi the Iceman, the famous mummified corpse pulled from a glacier in the Italian Alps, continues to keep many secrets. Now, through an autopsy like none other, scientists will attempt to unravel mysteries about this ancient mummy, revealing not only the details of Ötzi’s death but also an entire way of life. How did people live during Ötzi’s time, the Copper Age? What did they eat? What diseases did they cope with? Join NOVA as we defrost the ultimate time capsule—the 5,000-year-old man

In October 2007, a striking portrait of a young woman in Renaissance dress made world news headlines. Originally sold nine years before for around $20,000, the portrait is now thought to be an undiscovered masterwork by Leonardo da Vinci worth more than $100 million. How did cutting-edge imaging analysis help tie the portrait to Leonardo? NOVA meets a new breed of experts who are approaching "cold case" art mysteries as if they were crime scenes, determined to discover "who committed the art." And it follows art sleuths as they deploy new techniques to combat the multibillion-dollar criminal market in stolen and fraudulent art.

The dome that crowns Florence’s great cathedral of Santa Maria del Fiore—the Duomo—is a towering masterpiece of Renaissance ingenuity and an enduring source of mystery. Still the largest masonry dome on earth after more than six centuries, it is taller than the Statue of Liberty and weighs as much as an average cruise ship. Historians and engineers have long debated how its secretive architect, Filippo Brunelleschi, managed to keep the dome perfectly aligned and symmetrical as the sides rose and converged toward the center, 40 stories above the cathedral floor. His laborers toiled without safety nets, applying novel, untried methods. Over 4 million bricks might collapse at any moment—and we still don’t understand how Brunelleschi prevented it. To test the latest theories, a team of U.S. master bricklayers will help build a unique experimental model Duomo using period techniques. Will it stay intact during the final precarious stages of closing over the top of the dome?