Sean and Christian have relocated their practice from Miami to Los Angeles. Being new to the city they find themselves having to start from scratch business wise. What they thought would naturally fall into place turns out to require some foot work. So Christian and Sean hit the town and begin discovering a whole new world.

Sean and Christian learn about the glamorous side of fame and the price that many are willing to pay for it. Julia visits Sean, Christian and Liz in Los Angeles with a surprise announcement.

Sean and Julia learn more about their new family dynamic as Sean resists Eden's advances. Kate reveals a secret compulsion. Matt comes to Los Angeles with some troubling news for his fathers.

A series of unfortunate events unfold for an unlucky Dawn Budge, who seeks reparative surgery from Sean and Christian. Annie and Eden start to form a sisterly bond, which unnerves Sean.

A patient inspires Sean to take his relationship with Kate in a new direction. Eden uses extreme methods to persuade Christian to perform surgery on a friend. Kimber reaches out to an former business associate when she and Matt fall on hard times.

Sean's role on Hearts & Scalpels is expanded after he takes on an agent. A suspicious Christian questions Gina's motives for moving to Los Angeles and working at McNamara/Troy.

Sean experiences the ugly side of Hollywood in the form of a television critic. Matt experiences a special bond with one of Christian's patients. The cause of Julia's ailing health is discovered.