The Straw Hats without Luffy, Chopper, and Jimbei are taken to the laboratory on the clouds far above the ground by Lilith. They get excited about the things they've never seen before. However, inside the laboratory, a new threat is waiting for them.

Nami and the others are attacked by a Pacifista who resembles Jimbei and while they’re in battle, some of Vegapunk’s Satellites look on with excitement. Meanwhile, Luffy and the others find something extraordinary at the scrap heap.

Vegapunk asks the Straw Hats to take him on board their ship which makes Franky and Usopp happy but annoys Nami. Lucci orders his troops to block off all Vegapunk’s escape routes and looks to invade the heavily-secured Labophase.

The Seraphim come following CP-0 to the Labophase, pitting Zoro and Brook against the seven of them. Sanji, Franky, Edison, and Lilith leave the lab to fight them, but the Seraphim launch a full-scale attack on the lab.

Stussy suddenly knocked out Lucci to the Straw Hats’ surprise, and when Shaka reveals her true identity, they’re stunned again. Meanwhile, a major incident occurs on an island called Sphinx where Whitebeard came from.

CP-0 takes control of the Fabriophase but gets attacked by an unknown force. Meanwhile, in the Labophase, the Straw Hats and Dr. Vegapunk’s Satellites find out that Vegapunk has disappeared and begin searching for him.

Bonney witnesses her father Bartholomew Kuma’s painful memories. Meanwhile at the lab, Shaka notices that their communications and surveillance cameras are being cut off by somebody.

Lucci and Kaku from CP-0, who came to Egghead with a mission to eliminate the seven Vegapunks, ask Luffy and Zoro to uncuff them so they can fight alongside them against the Seraphim, but Luffy and Zoro are reluctant to do so.

The Straw Hats and CP-0 relentlessly attack the Seraphim, but the Seraphim keep getting back up. Then, Zoro notices that the Seraphim remind him of someone who he fought before. Meanwhile, Shaka goes to check one place where he thinks Vegapunk Stella might be.

Stussy and Sentomaru discuss how big the threat that closes in on Egghead is as Luffy and the others keep fighting the uncontrollable Seraphim. Meanwhile, in an underground lab, someone approaches Vegapunk, who is being held captive.

Kid gives his crew a pep talk before the battle with Shanks. And Shanks also prepares for the battle but learns how his own subordinates do as they like to protect their beloved boss. Finally, Kid has his Damned Punk ready to shoot.