When Squidward gets hurt on the job, he menaces to take legal action unless his employer, Mr. Krabs, agrees to cater to him to his every need. Mr. Krabs, who eventually gets tired of doing everything for Squidward, hires SpongeBob and Patrick to investigate the scene.

Mr. Krabs and Plankton, his business rival and Chum Bucket owner, set out to find clues on why they have no customers. The enemies find a common enemy—a popular new restaurant—in which they must work together to steal the secret formula of its "Flabby Patty" burgers.

Instead of paying money to repair a hole in the wall of the Krusty Krab, Mr. Krabs decides to use it to gain more income by turning it into a drive-thru window. However, his two employees, SpongeBob and Squidward, have difficulty in keeping up with orders, which results to wreak havoc.

SpongeBob gets driving lessons from the son of a legendary race-car driver, Tony Fast Jr.

SpongeBob and Patrick decide to build an indoor miniature golf course in SpongeBob's pineapple house after it has rained outside. Squidward, who was sleeping and annoyed, tells the two to keep the noise down in constructing the course. They must not disturb Squidward, while Patrick distracts SpongeBob to make him lose in the process.

Squidward becomes concerned when Patrick convinces SpongeBob that he needs to become more sentimental.

SpongeBob and the gang, including Patrick, Mr. Krabs, Squidward, Sandy Cheeks, Plankton and Karen, and Gary, participate in a sled worm race for one million dollars. However, just before the race begins, Plankton sneaks off to the Krusty Krab and uses a robot as his replacement in the race. Plankton goes inside the Krusty Krab to steal the Krabby Patty formula, while the group must keep a yeti, who is attacking them, away.

When Patrick suddenly grows a beard, he decides it is time to act like a grown-up. He tags along with Squiward, who offers to teach him everything he knows about how to be mature, much to SpongeBob's dismay.

While preparing to give an oral report for boating school, SpongeBob comes down with stage fright. SpongeBob asks Sandy for help, and receives a pair of goggles that would enable him to see people in their undergarments, so he will not feel nervous. However, in his oral presentation, his goggles malfunction, which makes SpongeBob to panic and run out with a boatmobile. Beating the red light, it calls the attention of a police, who starts chasing after him.

Plankton tries to befriend Squidward in order to get the Krabby Patty secret formula. However, Squidward refuses to discourse with him until SpongeBob tells Plankton that he must compliment Squidward's music in order to strike up a friendship. The two become friends and share their music to all of Bikini Bottom.

When doing arts and crafts with his best friend SpongeBob, Patrick is coveted by everyone in town after an art critic praises his artwork. He soon becomes a famous artist, which makes Squidward jealous. When he reaches an artist's block, Patrick must find new inspirations for his next masterpiece.

SpongeBob invites Mr. Krabs, Pearl, Sandy, Mrs. Puff, Larry, Squidward, and Plankton to watch a slideshow of his family vacation to the Great Barrier Reef. In the slideshow, SpongeBob and his parents are on a family road trip with Patrick, but the two best friends get lost and end up in a forest for adventure.

When feeling that he is doing the same activities every day, Patrick moans that he needs a break. SpongeBob suggests a vacation out of town, which cheers him. When at a travel agency, Patrick is given options, but they are thrown out when it is revealed that he cannot afford a trip. SpongeBob comes up with a solution—a "staycation", a vacation at home—which delights Patrick.

Mr. Krabs and SpongeBob win free tickets to a cruise, thanks to Plankton, but they do not know that it is a secret plan to steal the Krabby Patty formula. At the same time, Plankton tricks his computer wife Karen for a vacation, and she is initially excited until when she realizes that this is part of his plan to steal the formula. He lies to her and the both hop on the same cruise as Mr. Krabs and SpongeBob.

SpongeBob meets Sandy, who is preparing her rocket to go to the Moon for a vacation. However, SpongeBob accidentally stows away, and when on the Moon, the two set out camp. SpongeBob and Sandy play sports including sandboarding on its craters. After accidentally crashing the sandboard into the fuel tank, they immediately start the rocket because they need to return home before the fuel runs out.

Mr. Krabs takes a vacation with SpongeBob and Pearl to the Bikini Bottom Mint. However, his daughter does not want to tag along, so she stays at a museum. SpongeBob and Mr. Krabs proceed inside the mint, but the tour guide is instantly annoyed by their antics. When two bank robbers seize the mint, SpongeBob and Mr. Krabs stop them and they are rewarded with a special edition one-dollar bill with their faces on it, but Pearl confiscates the dollars and spends them on a new pair of shoes, causing Mr. Krabs to blast endless tear beams in the mint.

SpongeBob and Patrick find a houseboat haunted by a crew of ghost pirates headed by Lord Poltergeist. The two get caught in a feud between them and the Flying Dutchman.

SpongeBob and Patrick learn the secret origins of Mermaid Man and Barnacle Boy from the heroes themselves.

Plankton grows himself another eye because he lacks depth perception. However, it changes his personality and causes him to be nice, because the eye is from SpongeBob's DNA.

The night before a school dance, Pearl gets a barnacle on her face. Mr. Krabs asks SpongeBob to help his daughter remove the blemish to save money, instead of taking Pearl to expensive treatment.

When SpongeBob gets an invitation to his Grandma's birthday party, he asks his best friend Patrick to pet-sit Gary. However, Patrick only causes trouble, which makes SpongeBob angry.

SpongeBob gladly accepts to house sit Sandy's Treedome, while she is away. Sandy first shows SpongeBob what he should do, and all is quiet until Patrick arrives for a visit. The best friend causes chaos and wreak havoc, which results to the house getting destroyed.

Squidward and SpongeBob win backstage passes and tickets to Kelpy G's live concert. However, Patrick eats their passes shortly after the concert begins. Losing their passes, SpongeBob and Squidward try to sneak backstage to meet Kelpy G.

After making bubbles with hot sauce, SpongeBob and Patrick accidentally destroy Sandy's air supply by causing a fire and fill her Treedome with water by contaminating it. They must help her find enough oxygen in order to help them breath. In the end, SpongeBob goes to the surface to create a giant air-filled bubble, and puts it into the Treedome.

Sandy introduces Fuzzy Acorns, "the greatest karate master ever", to SpongeBob. The master is training Sandy to earn the "blacker belt", the highest belt in karate. SpongeBob wishes he had a belt, which Fuzzy overhears and tells SpongeBob that if he wants one, he has to earn it. Fuzzy offers to train SpongeBob so that he can earn the belt, which he reluctantly accepts.

While looking for spare change, Mr. Krabs notices an over-sized soybean at Sandy's Treedome. Mr. Krabs is interested in what could have enlarged the plant, and Sandy revealed an experimental growth formula, which Mr. Krabs steals out of sight. At the Krusty Krab, he uses the growth formula on a Krabby Patty, but it keeps on growing until chaos erupts.

SpongeBob receives a letter from an old friend Bubble Buddy, asking to babysit his son Shiny, who causes mischievous antics. SpongeBob must keep Shiny out of trouble and away from sharp and pointy edges.

A fed-up Squidward has had it with SpongeBob's annoying antics, pranks, wisecracks, and practical jokes and issues SpongeBob a restraining order against his neighbor. SpongeBob is afraid that he will violate the restraining order again. (According to this restraining order, SpongeBob is not allowed to come within 15 feet of Squidward, lest he end up going to jail for the rest of his life.)

Squidward discovers a piece of art by an artist named "Fiasco", and Mr. Krabs decides to use it as an attraction to his customers at the Krusty Krab. But soon after, Plankton steals it, believing he can reverse engineer the Krabby Patty formula from it.

Squidward tries to find his happiest memory, but gives up after hope is lost. Desperately, SpongeBob "helps" him create one.

SpongeBob and Sandy battle an evil Jellyfish overlord, who is replacing everyone in town with clones. After searching for clues, they figure out that its weakness is mayonnaise.

Plotting to ruin Mr. Krabs, Plankton, his business rival, drives away his customers. As a result, Mr. Krabs is forced to give out free Krabby Patties in order to try to win them back.

SpongeBob's pineapple house is falling apart and is in needing repairs, so he gets all of his friends to help him refurbish it. However, despite the big changes, SpongeBob is not happy with it. In the end, his pet snail Gary helps him with his can, which contains a fully furnished pineapple.

When Plankton replaces his computer wife Karen with an upgrade called Karen 2.0, the original Karen leaves and gets a job at the Krusty Krab.

SpongeBob has difficulty falling asleep, while Patrick struggles to stay awake.

SpongeBob and Patrick get face freeze after making too many faces despite being warned not to by Mr. Krabs.

SpongeBob and Patrick spend a final day at Glove World before it shuts down forever, only for a new amusement park called Glove Universe to open.

When Squidward goes home sick with a fake illness, SpongeBob thinks he has caught it for real.

Mrs. Puff enters SpongeBob into a demolition derby, but SpongeBob's awful driving makes him a superstar.

SpongeBob brings home a box of new snail treats that Gary will do anything to get – especially when they run out.

Mr. Krabs organizes a guessing game to his customers at the Krusty Krab for a Krabby Patty. When Plankton tries it, he actually wins. Mr. Krabs will do anything to stop him from collecting his prize.

Plankton turns everybody in Bikini Bottom from nice to naughty by feeding them his special jerktonium-laced fruitcakes and transforming them into donkeys in his attempt to get his Christmas wish—the Krabby Patty secret formula. However, it is revealed that the only victim capable of surviving the mineral is SpongeBob because of his massive love for the holidays which makes him immune to the effects of jerktonium.

Plankton teams up with Man Ray to get the Krabby Patty formula and rule the world.

Squidward quits the Krusty Krab to work for Plankton, turning the Chum Bucket into an overnight success.

Mr. Krabs wants all of Bikini Bottom to eat at the Krusty Krab, so SpongeBob and Patrick go on an advertising blitz.

Mr. Krabs and Plankton circulate petitions about the bulldozing of a Bikini Bottom restaurant.

A concert promoter named Colonel Carper wants SpongeBob and Squidward to form a band together and send them on a "world tour". However, the greedy Mr. Krabs decides to manage them in order to make his own profits from his to employees' success.