While the Turtles are busy evading Bonesteel, an old enemy of Chung I's arrives in New York to destroy Chung I's former student: Venus.

Raphael and the Turtles go against the wishes of Venus and Splinter and return Vam Mi's heart. Yet the vampires are determined to destroy Venus.

Bonesteel is sick and tired of the immortal bloodsuckers getting in the way of his efforts to capture the Turtles.

With the Turtles being held hostage by Bonesteel, it's up to Splinter and Venus to defeat the vampires once and for all.