The Turtles barely escaped the last time they were confronted by Dragon Lord. Now their nemesis has stolen the coveted Serum of Invincibility!

Donatello and Venus have very different ideas regarding how to neutralize the Serum of Invincibility.

One of Donatello's biggest idols in the world of science, Dr. Quease, is kidnapped by the dragons.

When the Turtles stumble upon a man being attacked by dragons in Central Park, they are shocked to learn they've rescued someone from their past!

While the Turtles are busy evading Bonesteel, an old enemy of Chung I's arrives in New York to destroy Chung I's former student: Venus.

Raphael and the Turtles go against the wishes of Venus and Splinter and return Vam Mi's heart. Yet the vampires are determined to destroy Venus.

Bonesteel is sick and tired of the immortal bloodsuckers getting in the way of his efforts to capture the Turtles.

With the Turtles being held hostage by Bonesteel, it's up to Splinter and Venus to defeat the vampires once and for all.