The Transporter's package is a beautiful young woman who's caught in the crossfire between her disgraced General father, and the criminal syndicate hunting him.

Frank faces a dilemma when he finds out his package is a heart meant for transplantation stolen by his crime lord client to save his own son and when Inspector Tarconi informs him that another dying boy is waiting for it at the hospital.

Frank is hired to bring a package from the south of France to Paris. Once there, he realizes the package is a bomb meant for a planned terrorist attack.

Frank has to transport a young hacker to her new employer. But the employer is not the only one that is interested in the girl. Meanwhile, Frank has a lunch date with Juliette that doesn't exactly turn out to become a romantic moment.