Nonnatus House welcomes a new recruit, Nurse Valerie Dyer. A vulnerable young man captures Fred and Violet's hearts, whilst the whereabouts of Sister Mary Cynthia is a concern.

An unexpected turn of events leads to a wedding being hastily arranged. Shelagh finally goes into labour. The arrival of the pill leads to unforeseen consequences.

Boxing Day sees heavy snowfall covering the country and the adverse weather causes major disruption across Poplar as roads become blocked and pipes freeze meaning families have to queue outside for water from standpipes. Sister Julienne must inform a family about the death of their loved one and uncovers an uncomfortable truth, while Valerie helps an unmarried couple living in a caravan prepare for their baby, but unforeseen complications knock her confidence in her ability as a midwife. Guest starring Anita Dobson.

The winter continues, and the team at Nonnatus House welcome their newest midwife, Lucille Anderson. Nurse Crane and Dr Turner care for an elderly cancer patient facing eviction.

Lucille must win the trust of a mother who is terrified of giving birth. Nurse Crane and Dr Turner are anxious to find a possible smallpox sufferer.

The team must rally to prepare for Sister Monica Joan's birthday. Meanwhile, the closing of a nearby maternity home brings an influx of expectant mothers to the Nonnatus midwives.

As Poplar prepares for Christmas, the nuns leave for the Mother House to vote in a new mother superior and to help care for a group of Chinese orphans. Meanwhile, Trixie returns to Poplar refreshed and is shocked to discover that many mothers no longer want to give birth at home.

Valerie helps a struggling mother accept her son's birth defect. The Turners oversee a measles vaccination trial at the clinic as the team prepare for the Whitsun bank holiday.

Sister Hilda digs deep to give her terminally-ill patient her final wish whilst the Turners must prepare to say goodbye to May. Fred and Reggie are keeping secrets from each other.

Mother Mildred and the Nonnatus House team head to the Outer Hebrides in response to a nursing shortage.

Sister Julienne volunteers to put up four trainee doctors at Nonnatus House while they undertake the practical aspect of their obstetrics diploma, hoping the exercise will remind the council how vital the home is to the community and help remove the threat of demolition.

At the Turners, Shelagh receives a phone call from the Hong Kong adoption agency, which has the alarming news that someone from May's past has arrived in the UK and wants to see the little girl.

Sister Julienne decides it is time to take matters in hand when a letter arrives from the council saying that it will cut funding to Nonnatus House and no longer pay for the accommodation, and goes to see Violet at one of her open sessions as a local councillor.

The circus comes to Poplar, putting a magical spell on its residents. A delighted Shelagh is reacquainted with an old friend, and Trixie receives an unusual gift.

It’s July 1966, and Britain is in the grip of World Cup fever. New pupil midwife Nancy makes quite an impact.

Nonnatus House struggles to come to terms with Nancy’s revelation. With Sister Julienne taking her annual leave at the Mother House, Sister Hilda relishes the chance to cover and impress with her leadership.

While attending an expectant mother, Sister Frances and Trixie are appalled to learn that Poplar’s housing crisis is worsening, leaving the Nonnatus team vowing to fight for change.

It’s a poignant time for the Turner family as Timothy readies to leave for medical school in Edinburgh and Cyril receives news from home, prompting him and Lucille to consider their own future.

Meanwhile, a very special baby is born, who causes a rift in a close-knit family and leads many people to count their blessings.

Christmas promises to be a memorable one at Nonnatus House as Lucille and Cyril prepare for their upcoming winter wedding. The Nonnatus team are faced with their busiest Christmas Day ever as the Maternity Home is filled with expectant mums-to-be, each with their own challenging case. Luckily Mother Mildred is on hand to support the team.

Demolition work in Poplar uncovers a long-buried secret that leads to a testing and emotional case for the team. Sister Julienne takes on a sensitive delivery.

Sister Hilda and Dr Turner support a young father with a lung condition whose wife is planning a home birth, and discover he is also coping with the repercussions of a past trauma. Cyril looks for a job that will put his qualifications to good use, a first-time mother struggles to bond with her daughter, and Fred comes up with a way to keep the wards cool during a summer heatwave.

Nonnatus House suffers its biggest threat yet. But this time it’s not the bricks and mortar that are in danger, it’s the people.

Nonnatus House faces its darkest day after a tragic incident in the heart of Poplar. As the community rallies together, the team must overcome personal anguish to help the injured.

The Turners support a family still suffering the devastating effects of thalidomide, Miss Higgins is involved in an unexpected delivery, and the community stages a talent show.

The maternity home is thrown into chaos by an outbreak of gastroenteritis, and Nurse Crane fights to save her career. Meanwhile, Cyril encourages Reggie to seek help.

A pregnant mother with a chronic heart condition falls unwell, Nancy grows suspicious of a young father’s erratic behaviour, and Matthew prepares for a visit from his father.

Trixie supports an underage mother through a difficult time, Monica Joan welcomes an unusual guest to Nonnatus House, and Sister Veronica spearheads a new council initiative.

Dr Turner experiences the biggest test of his career, while Trixie’s approaching nuptials cause stress levels to escalate. Sister Julienne hatches a plan to save Nonnatus House.

As Poplar prepares for Christmas, Sister Monica Joan fears this could be her last. Dr Turner and the midwives deal with a complicated multiple birth, and Cyril helps a war veteran.

Sister Julienne cares for an expectant mother who has cerebral palsy. Nonnatus House kicks off its new midwifery training scheme with the arrival of four new pupil midwives.

Nurse Crane helps a struggling first-time mother accept her baby’s birth defect, and Violet’s bid to be mayor is thrown into turmoil by unforeseen circumstances.