The police officers of the Sant'Andrea police station investigate a gang specializing in robberies in supermarkets. During the investigation, the policeman Tommaso De Rosa, who monitored the movements of the suspects, was killed.

A man shows up at the police station to report the disappearance of his daughter: Inspector Elena Baroni will investigate the case. Meanwhile, the search for the culprit in Tommaso De Rosa's death continues and Commissioner Cafasso reveals his suspicions about a colleague of theirs to Inspector Pietro Guerra.

Alfredo Spinosi, owner of a building company, is found dead. The investigation will lead to a swinger club tour.

An explosion of malicious origin took place in the house of a Neapolitan merchant: Guerra understands that the shopkeepers in the neighborhood where the merchant lives are all victims of extortion by a felon. During the investigation, the commissioner will discover that even one of his men is corrupt and has ties to the local underworld.

Agent Paolo Esposito, whose involvement in the affairs of the underworld was discovered by Guerra, decides to collaborate with the judiciary, but to improve his position he has Sanniti, head of the organization in which he was an accomplice, indicted. Angelo, a friend of the agent Stefano Depretis, is killed with the pistol stolen from the superintendent Antonio Ramaglia.

Antonio Arena, accused years earlier by Inspector Guerra on charges of pedophilia, is shot dead while walking through the streets of Naples. While Guerra and Baroni investigate, another offender awaiting appeal is killed, on whom the same charge was pending. In the second episode, agent Sergio Amato realizes that he has fallen in love with the prostitute with whom he spends many evenings and when he learns that she has been beaten by her pimp, he decides to intervene.

A child is run over by an Alfa 33 which runs away without helping him: the agents investigate to discover the identity of the hit-and-run driver. Sandro Scano, murderer of his wife, has been released from prison and wants to take revenge on Inspector Guerra.

The superintendent Sergio Amato is looking for Lele, a guest of a therapeutic community who disappeared. When the boy's lifeless body is found, inspectors Baroni and Guerra also take over the investigation. In the meantime, Pietro thinks of leaving the police to be able to devote himself more to his wife and family.

An elderly lady is found murdered together with her friend in an apartment. Inspector Baroni is investigating the case, supported by agent De Pretis. Sergio meanwhile does everything to try to get Tania a residence permit. During the investigation into the murder of the two ladies, agent Laura Onorato shoots a criminal, killing him.

A young couple has just got married, but a burst of machine gun fire on the wall of the Church breaks their joy. This is a warning, but to find out who it is addressed to, Inspector Guerra and the Superintendent of Investigation Amato will have to intervene. To complicate the case, a woman's complaint against Father Mauro takes over.

On the outskirts of Naples, a girl is found covered in blood and in a state of shock: Guerra and Baroni will investigate the matter, while Amato is demoted to archivist of the deputy commissioner Cafasso due to his coexistence with Tania. Agent Nava, in the second episode, decides to infiltrate the religious sect he is investigating.

Carmelo Battisti issued false residence permits to young black people by exploiting their work: Commissioner Baroni investigates the case. Some police officers instead deal with the case of a bank manager who steals money from the coffers.

The first case of the episode seems to be a settlement of accounts: a man is wounded by a hitman and, during the investigation, the involvement of a dangerous fugitive emerges. Superintendent Amato, readmitted to the team, must go to an old factory where shots have been heard.

Three men break the hand of a boxer named Santo Lucci and Guerra and Amato take on the case. Guerra hires the daughter of the deputy commissioner, Daniela Cafasso, as a babysitter for her children. Fabrizio Nava and Laura Onorato instead investigate a suspicious coming and going from an apartment.

Agent De Pretis infiltrates a gang of counterfeiters to be able to catch them red-handed and arrest them. Inspector Baroni instead investigates the murder of a young thief, shot dead by the owner of a shop exasperated by the constant thefts.

The agents come across an abandoned crashed car: they identify the injured owner, who gives extremely vague explanations of what happened. The Bandinis, for whom the lady is a custodian in Pozzuoli, receive threats from strangers and turn scared to the Sant'Andrea police station.

A doctor is shot while driving in his garage. The surgeon is wounded and Pietro, Sergio and Stefano investigate the various leads: is it a terrorist attack, a crime of passion or is there a professional motive?

The body of Alice Orefice, 12 years old, is found on the beach of Vico Equense. Emanuela, a friend of hers, confesses that she is aware of Alice's relationship with a grown man. Elena Baroni, meanwhile, is hosting a friend of hers who is being blackmailed by a trafficker in the area because of a debt.

Two wealthy spouses are bound and gagged by three men in their apartment. It turns out that the theft is not the first one perpetrated in the same way. A new investigator joins the Sant'Andrea police team: Edoardo Valle.

When leaving a supermarket, a mother can no longer find her four-year-old son: Pietro and Elena discover an abusive ex-husband in the woman's past. Meanwhile, Sergio discovers that Tania is HIV positive and Laura and Fabrizio see emotional problems negatively affecting their professional activity.

In the trunk of an abandoned car, the discovery of the body of a 26-year-old girl, Mirella Cuomo, murdered with stabs and with her left ring finger amputated. From the first investigations it emerges that the girl was the girlfriend of a well-known repentant offender.

Elena Baroni deals with a case of rape: during the investigation it turns out that the rapist had previously raped another woman. Laura Onorato manages to discover a drug dealing ring in a nightclub.

A bomb placed in a car causes the car to explode and injure a young policewoman. Cafasso discovers that the bomb attack was actually directed against two Camorristi and, with the help of a magistrate, traces back to the principal: he is the head of a clan, who is hiding in a villa.

Carlotta Santarcangelo, in revenge for her father's arrest, shoots Fabrizio, who falls into a coma. Colleagues mobilize to frame Santarcangelo, accused of mafia association. Meanwhile Pietro investigates the mysterious death of a woman in a women's prison: after discovering that Irene Scotti was pregnant with her, the inspector suspects sexual assault resulting in murder to avoid scandals.

The Sant'Andrea police station is involved in the investigation of a triple murder case: a hairdresser, killed after being savagely beaten; the owner of a car repair shop, tortured with a blowtorch; a suffocated car dealer who, before dying, had time to carve a cross on a door.

A stand-up comedian is found murdered in a television studio: inspectors Guerra and Baroni are investigating the complicated case. Meanwhile, a teacher sees a Chinese child returning to class with a seriously injured hand: the police suspect it is an accident at work.

The body of a girl from Naples' upper class is found on a beach in the city. Only one clue: on the victim's cell phone, a message from her boyfriend who arranged to meet her in that place. When questioned by Pietro, the boy says he knows nothing about the message, that he has lost his cell phone and that he has an alibi: at the time of the murder, he was at a soccer game with friends.

The day after the violent explosion at Sant'Andrea, the policemen share a deep sorrow and the angry desire to capture the person responsible. The question arises about the true identity of the accountant who died in the terrible ambush together with the group of criminals who infiltrated to free him, what facts did he know?

An elderly man arrives at the police station to report the discovery of a fanny pack containing a lot of money and a notebook with indecipherable notes. Alfio and Antonio discover that the man is an internationally renowned university professor and immediately speak to Cafasso. What is the relationship between an apparently honest professor and the Camorra?

A blood-stained bedroom, the lifeless bodies of a man and a woman, a new complicated case for the agents of the Sant' Andrea police station. At the crime scene there is no sign of violation, but the killer left his traces on a protruding screw.

A boy who arrived in Naples from South America is taken to the emergency room for a serious illness. Sciacca and Silla, who rushed to the hospital, learn that the young man had cocaine pellets in his stomach and that, surprisingly, he asked to file a complaint.

A man is suddenly killed on the platform of a train station just before the arrival of the train he was waiting for. Dr. Veneziani, who rushed to the scene of the murder together with Sciacca and De Luca, finds a briefcase containing a gun.

After the discovery of the body of a man of Chinese origin, Dr. Veneziani begins the investigation at the crime scene. Pettenella, Walter and Pietro think of a possible war between the Camorra and the Chinese mafia. All possible investigative leads must be pursued and Anna tries to investigate what is happening within the Chinese community.

A man lies lifeless on the ground with scissors stuck in his throat, a possible macabre signal sent by the Camorra to indicate that he had talked too much and therefore deserved that tragic end. Walter, arriving at the scene of the murder, recognizes his informant: the tailor Ilario Bigi.

Having entered the lair of the boss Annibale Ruotolo, the police find that the apartment is empty and there is no trace of the Camorrista. Did the boss understand what their plan was or is there a mole who has spilled the beans? Someone made Anna disappear, who recently pretended to be a corrupt policewoman to allow our men to capture Ruotolo.

A young boy, who Antonio helped in the past to get out of the drug scene and who joined an association for the recovery of young people at risk, goes to the police station to ask for help: his stepfather, a criminal with violent behavior, has been released from prison thanks to a pardon and now represents a threat to him.

The investigations continue to capture the boss Annibale Ruotolo. After discovering that the ambush set on Ruotolo two years earlier was organized by Vincenzo Matrone, an old acquaintance of Sant' Andrea, the new vice-questor Tiziana Torre and the commissioner Pettenella ask the magistrate for authorization to meet the young Camorrista in prison.

While Cafasso and the men of the Bellini police station are still at sea with the investigation into the murder of a black prostitute, a new crime similar to the first unexpectedly occurs. This time the agents of the Sant' Andrea are dealing with it: a Nigerian prostitute, killed with two shots to the heart, lies motionless in the arms of a boy who does not want to separate from her.

The men of Sant'Andrea and those of the Bellini police station, led by Cafasso, continue to investigate the deaths of Nigerian prostitutes, their pimps and their customer base. The prime suspect in the murders, however, is found dead in his home. Dr. Mari's autopsy quickly reveals that the alleged serial killer did not commit suicide but was murdered.

Mafia boss Vincenzo Matrone has escaped from the rehabilitation clinic where he was hospitalized. A young policeman, the only guard on duty for the boss at the time of his disappearance, becomes the scapegoat because he had left the room for a few minutes in order to help a nurse dealing with a woman in a coma.

Antonio and Demetrio question the colleagues of a worker who fell from a scaffolding at the port and who is now hospitalized in serious conditions. No one knows why the worker was up there and there appear to be no witnesses to the accident. The investigators suspect an attempted suicide to collect the insurance, the doctors find a wound to the man's head caused by a metal edge.

Following the failure of an important operation, Cafasso is convinced that the mole hidden in the Bellini police station is Commissioner Livia Palma. In fact, a call was made from her phone to a mysterious cell phone, registered to a dead man. A number activated immediately after the escape of the boss Vincenzo Matrone.

A fire breaks out in an illegal parking lot, among the cars on fire is that of the manager of a private company that manages the water supply. The Sant'Andrea agents discover from the bank records that the woman regularly pays protection money and near the manager's office the body of a worker is found.

The men of Sant'Andrea are dealing with a raid inside a nightclub. After intercepting some drug dealings and guarding the entrances to the club, the policemen move on to searches. Among the many young people stopped and taken to the police station, there is a student who reacts desperately: a small bag of cocaine was found in her bag and she declares that she does not know who could have put it.

The body of a girl is found in the waters of a canal. No documents, no signs that could lead to her identity. A young man, recognizing the photo in the newspaper, reveals to the men of the investigation that he had met the victim the day before. She was an Argentine journalist who intended to write an important investigation by collecting numerous testimonies.

A jeweler is robbed by two boys disguised as workers, impossible to trace their identities: the man was unable to see their faces. An interesting detail emerges from the surveillance cameras: one of the two robbers was wearing a cap with the logo of a yacht club. Ramaglia goes to the nautical club and discovers that among the young people of the reformatory who make clothing for the yacht club there are three old acquaintances of Sant'Andrea.

The lifeless body of a psychologist, a well-known university professor, is found in a peripheral area of ​​the city. Digging into his private life reveals a homosexual relationship with a young researcher. The boy, an old acquaintance of Simone, appears very willing to collaborate. The young man claims to have an alibi but this is not very reliable, therefore he is accused of the murder.

A well-known lawyer is robbed by a woman in a balaclava. A man catches a young boy in his apartment, and the same man is robbed a few hours later while walking down the street. The men on the team work to find a common denominator for all these crimes.

In the living room of a villa lie the bodies of three women with their throats cut: a mother, a daughter, and a neighbor. On the landing of the upper floor a man is fighting for his life, also in a pool of blood. No sign of forced entry and nothing to suggest an attempted theft.

At a bus stop a thief tries to snatch a purse from an elderly woman. Most of the bystanders pretend nothing is happening while a man, shocked by what is happening, confronts the criminal. With the assault report and the identikit obtained thanks to his testimony it will not be difficult for the men of Sant'Andrea to identify the thief.

During the dress rehearsal of a Neapolitan skit, a stage gun actually fires. The protagonist collapses lifeless on the ground and never gets up again. It is immediately clear that someone has replaced the fake gun with a real, loaded one. The investigation at the Sant'Andrea police station unfolds in an environment full of poison, intrigue and ambition.

Nine months have passed since the last investigation and in this time frame many balances have changed at Sant' Andrea. Deputy Commissioner Tiziana Torre has been transferred and Giorgio Pettenella, who has just been promoted, has returned to take her place. There is a familiar atmosphere and the police station seems to have finally regained its former harmony.