Perry drives to the scene of a shooting and finds the police recovering the body of Harry Merrill from a car that went over the side of a mountain. MerriIl has a bullet in his body and a pillowcase over his head. Meanwhile, Perry's client, Evelyn Bagby, claims she was chased by a hooded man in a car near the same cliff that day. She fired two shots at the man's car to scare him off, and now the police want her for murder.

Ed Davenport learns that a sandwich he requested to be tested by a lab contains arsenic and blames his wife Myrna. When he confronts her about his suspicions she denies it. He leaves for a business trip and falls ill. Dr. Renault is called to treat him at a motel where Ed Davenport later dies. Before he dies he claims his wife poisoned some candy. After locking the motel room the doctor calls the police. The police arrive to find the corpse missing. The police test the candy and indeed find arsenic. Subsequently Ed Davenport's body is found in a shallow grave. Myrna Davenport is accused of the murder.

Restrauteur Morey Allen, a friend of Perry and Della's, has a problem: his waitress, Dixie Dayton, was struck by a car while fleeing the restaurant after spotting a man stalking her. The only item she left behind was a moth-eaten mink. When the stalker is found murdered, Morey and Dixie are both strong suspects and eventually get arrested for the murder. The case also ties in with the murder of a young policeman several months before.

Perry has to navigate his way through a hornet's nest of murder, hit-and-run, secret marriage, and a missing witness in this episode.

When wealthy Louise Gordon is poisoned to death her nurse is charged with the crime. Perry does some digging and discovers that the first wife of the victim's husband also died of poisoning. Is the husband really the culprit or could it be someone else?