R2-D2 is part of a team of Republic droids chosen for an important mission led by the diminutive Colonel Gascon to obtain an encryption module from a Separatist dreadnought. The droids must overcome numerous challenging obstacles to succeed in this crucial assignment.

After a comet damages their shuttle, R2-D2, Colonel Gascon, and the other droids crash on a desolate planet where they must make their way across a bewildering expanse of emptiness to carry out their mission.

In a nearly vacant town, R2-D2 and his team find a clone commando suffering from amnesia.

R2-D2 and his team must stop a sabotaged Jedi cruiser from destroying a crucial Republic conference.