Isabel visits Seville, Castile's richest city but also a place plagued by crime and corruption. Juan II accuses Fernando of caring more for his wife's kingdom than for his. A border incident sours relations between Castile and Granada.

The King's long absence throws Portugal in confusion, but Isabel and Fernando are no less divided over their next move. Rome pressures Castile to adopt the Inquisition. In Granada, the jealous Aixa plots against the Emir.

The converts of Seville look at their options in the face of the Inquisition. Juana's unruliness threatens the peace between Portugal and Castile. Beatriz learns her nephew's secret. Muley-Hacén names his heir.