Tommy starts taking Janet's antidepressants. When Sean meddles in Franco and Laura's troubled relationship he makes things worse. After a gay visitor, the crew wonders about Mike's sexuality.

Tommy copes with a tragedy. Jerry must decide what to do when his wife's condition worsens. Sean has a crisis of faith. Lou learns some shocking facts about Candy. And the crew responds to a multi-level building fire with people trapped inside.

Lou turns to new-age techniques in his efforts to change his life. Sean and Maggie come to a surprising decision. Tommy and Angie continue to see each other, which quickly leads to an embarrassing scene with Janet.

Janet plots revenge when she learns what Tommy did with the baby; Franco questions his marriage proposal to Natalie in light of Alicia and Keela's return; and Tommy faces his ghosts.

Tommy makes a shocking discovery regarding Jimmy's whereabouts on 9/11. Sheila takes drastic measures to purge the negative energy from her life as Sean's back pain gets worse. The bar, however, finally takes a turn for the best as the guys enjoy a fruitful opening night.

A late-night cleanup turns into a nightmare for Tommy when several unexpected visitors stop by the bar. Feinberg allows Damien to ride along with the crew, but may not be prepared for the consequences.

The guys visit Sean in the hospital; Katy is home from school and wants a family dinner---one that includes Colleen and Black Shawn; and Lou and Tommy make a wager concerning the women in their lives.

As Damien joins 62 Truck, Sheila reminds Tommy of his promise to watch out for him. Meanwhile, Janet gives Tommy guidelines for their relationship; the guys attend a memorial dedication for a firefighter who died on 9/11; and Sean is released from the hospital, vowing to live life "to the fullest."

The perfect party becomes a nightmare when a herd of brutish women infiltrate the bar. Tommy's love triangle reaches new heights.

Damian receives an offer that unsettles Tommy; Lou discusses his upcoming wedding plans with Tommy and Needles.

Tommy has rocky encounters with Janet and Sheila, and an encounter with Kelly that isn't as rocky. Meanwhile, the guys go grocery shopping with the newly domesticated Lou.