England, 1868. A thief tries to raid an overturned carriage, but discovers that two of the occupants, a man and his young son are still alive. The man, George Joestar, proclaims he will forever be indebted to his savior, who reveals himself to be Dario Brando.

Seven years later in 1888, JoJo and Dio are supposedly getting along, though JoJo is still fearful of Dio. Meanwhile, Dio plots to liberate the Joestar family of their fortune.

JoJo prepares to turn Dio in to the police.

Three days after the incident, JoJo awakens to find Erina nursing him back to health in the hospital. As they rekindle their friendship, they encounter a strange man named Will A. Zeppeli.

A talented young pickpocket named Poco unwittingly lures JoJo and company into an encounter with Dio, Tarukus, and Blueford.

The encounter between JoJo and the Knights continues.

The encounter against Tarukus comes to an end. Poco's family is in grave danger. JoJo meets Dire, Straizo, and Tonpetty.

The party are received by Doobie. Dire faces off against Dio. Straizo takes on Pajyu, Jones, Pluton, and Barnum.

As Dio falls following his battle with JoJo, he decapitates himself before the ripple reaches his head, which is recovered by his zombie servant Wang Chung.

In 1938, 49 years after Jonathan Joestar's death, Speedwagon and Straizo travel to Mexico, where they discover an underground room filled with similar looking masks and a petrified body believed to be the being who created them.

As expected, Straizo recovers from Joseph's attack and uses the laser eye attack Dio used to seemingly pierce through JoJo's head and neck. However, this turns out to be a clever trick by Joseph.

Joseph is confronted by one of Stroheim's men, Donovan, but manages to subdue him, learning that Speedwagon is still alive.

As Joseph begins to fight against Santana, Joseph finds his Ripple to not be effective against Santana, but it still helps protect him from the Pillar Man's attacks. Joseph appears to be unconscious after receiving a powerful hit.

Speedwagon brings statued remains of Santana to the headquarters of his foundation in Washington, D.C., where it is shown Santana is still alive, but his scientists are able to keep him dormant through the use of ultraviolet light.

Caesar engages Wamuu in battle for killing Mark, using his Bubble Launcher technique to surround the Pillar Man in Ripple enfused bubbles.

Wanting to teach JoJo to control his Ripple powers, Caesar takes him to Venice to meet his teacher, Lisa Lisa.

Lisa Lisa explains to JoJo and Caesar how the creator of the Stone Mask, Kars, is seeking a perfectly cut Red Stone of Aja known as the Super Aja to power the Stone Mask and become the ultimate life form.

As JoJo awaits to warn Lisa Lisa about the Pillar Men, Esidisi's brain takes over the body of Suzi Q and sends the Super Aja off on a boat bound for Venice before confronting Lisa Lisa.

Stroheim starts using his new mechanical body, which was designed to surpass Santana, to fight against Kars. However, it proves futile against Kars' Light Mode.

Lisa Lisa tells JoJo of Caesar's childhood, in which he took to crime at a young age after being abandoned by his debt-ridden father, Mario.

Whilst following Wamuu's trail of blood, JoJo and Lisa Lisa encounter another vampire named Wired Beck.

Before JoJo's and Wamuu's race begins, it is revealed that during each lap, there will be a different weapon for whoever can grab it from a pillar first.

Launching his Final Mode attack, Gathering Gale, which starts peeling away his own body, Wamuu begins firing a stream of wind capable of cutting stone towards JoJo.

Being forced to cling onto a rope to stop Lisa Lisa from falling to her death, JoJo is at a huge disadvantage against Kars.

Kars demonstrates his new powers, turning his hand into a flesh-eating squirrel that deals damage to Stroheim. The sun rises, leaving a shocking discovery.

JoJo's victory, along with his arm, is cut short when Kars manages to survive the volcano by forming a shield of air bubbles to protect him from its deadly lava.

In 1987, in Japan, a boy named Jotaro Kujo has willingly turned himself into jail, refusing to leave. Jotaro's mother, Holly, requests help from her father, Joseph Joestar, who travels to Japan alongside an acquaintance, Mohammed Abdul.

Jotaro heads to school and encounters a mysterious transfer student named Noriaki Kakyoin.

Jotaro is able to defeat Kakyoin. He takes the wounded Kakyoin back to his house, hoping to get some information about DIO.

If they do not defeat DIO within 50 days, Holly could die - Jotaro and crew head to Egypt, where they think DIO is hiding. While on the plane, they run into another one of DIO's assassins.

DIO's next assassin, Polnareff attacks Jotaro and crew, Abdul faces him with his Magician's Red.

With a new person in their party, they head to Singapore with the boat the Speedwagon Foundation provided them, during their journey Jotaro is targeted by an enemy Stand from within the water.

A giant ship shows itself. On board, they realize they can't seem to find a crew, but an orangutan.

Arrived in Singapore, Jotaro's group stays at a hotel individually. A new Stand owner who is known as "Devo the Cursed" is awaiting Polnareff in his room. Devo's Stand increases its power as its user's hatred towards the opponent increases. Polnareff gets into a desperate situation as he starts fighting front. Does Polnareff have a chance to win the battle against Devo who keeps attacking him in a cruel and brutal way?

Joseph uses Hermit Purple to create a message using the TV, which tells them that Kakyoin is a traitor.

The group travels to India. In a restaurant Polnareff is attacked by a mysterious Stand that is inside a mirror.

In an effort to save Polnareff, Abdul is injured by the enemy. Then J. Geil's Stand, Hanged Man attacks.

The group heads toward Varanasi. On the way, Joseph realizes his arm is quite swollen.

Jotaro and the others head toward Pakistan in a car. Polnareff is driving the car on a very dangerous mountain road, and recklessly passes a slow moving vehicle that was in front of him.

Jotaro and the others successfully survive another attack from the enemy Stand users and make it into Pakistan. However, they decide to find an inn at a nearby village because of the dense fog they suddenly hit. The village they get to is rather quiet and all of the inhabitants seem rather odd.

Polnareff finally realizes that Enyaba is another assassin from DIO. He tries to warn the others, but Enyaba's Stand, Justice, has the ability to take control of people's bodies and corpses, and he is pursued. The whole village had already been under Enyaba's control.

After surviving Enyaba's attack, Jotaro and crew make it to Pakistan's capital, Karachi. There, they encounter DIO's next assassin, Steely Dan. Following DIO's orders, Steely Dan ruthlessly kills Enyaba in front of them. Jotaro and the others can't help but feel conflicted about that happening, and end up in a battle with Steely Dan.

Steely Dan's Stand, The Lovers, has entered Joseph's brain. Dan puts himself at an advantage, with having Joseph's life on the line, and tells Jotaro to do various things for him, knowing Jotaro has no choice but to obey. Meanwhile, Kakyoin and Polnareff also enter Joseph's brain with their Stands and find the Stand that is using brain cells as food.

Jotaro and the others continue their journey through the desert, trying to get to Cairo. They travel with camels and can't shake the feeling that someone is following them, but no one is in sight. Traveling in the killer heat, they realize that it's still bright out at 8pm and the sun is actually rising rather than setting.

Kakyoin is dreaming and dreams about being in a strange amusement park, where he encounters the Death tarot card. While in the dream, he witnesses Death 13 cut down a dog. Kakyoin wakes up screaming, but can't remember what his bad dream was about.

Kakyoin tries to convince the others that the baby is suspicious, but that backfires and his friends start to doubt his sanity. Kakyoin then tries to convince them that he's not crazy, and shows them his arm that has "Baby Stand" carved into it... but that just makes them believe he really is crazy. Kakyoin then tries to use his Stand to attack, but is knocked out by Polnareff. Eventually, Jotaro and the others wake up in the nightmare and the truth finally comes out.

While on an island on the edge of the Red Sea where Mohammed Abdul's father is said to live, Polnareff uncovers a magic lamp and its genie Cameo offers him three wishes, although all is not as it seems. 

Polnareff must find out a way to escape the attacks of Cameo and his Stand Judgement who has apparently turned his sister Cherie and Abdul into zombies.

Jotaro and the others obtain a submarine as a new means of travel. Through the Red Sea, they try to head toward Egypt where DIO awaits. Using the sonar to detect any threats on the outside, the submarine quietly dives in. They however realize that if they're attacked underwater, there is nowhere to escape, so they are on their guard. Finally, when they are about to surface, a coffee mug that was in the cabin transforms and cuts off Joseph's artificial hand.

The group must find a way off of the submarine and away from the attacks of High Priestess. 

Jotaro's group encounters N'Doul's Stand "Geb", and Iggy's "The Fool".

The group's encounter with "Geb" and "The Fool" continues.

As the Joestar group arrives in Aswan they encounter Oingo's Stand "Khnum" and Boingo's Stand "Thoth".

Jotaro's group encounters the Stand "Anubis".

The encounter with the Stand "Anubis" continues.

Jotaro and the others arrive in Luxor. While heading there, Joseph notices an electrical outlet in a rock. Obviously fascinated by the electrical outlet in the rock, Joseph gets closer, and he gets shocked.

Due to the powers of an enemy Stand, Joseph's body becomes magnetised. While chasing after the woman that seemed to be the Stand user, Abdul also touches the electrical outlet and becomes magnetised as well.

While Joseph and Avdol were fighting with Mariah, Jotaro gets concerned that they haven't shown up yet, and goes to look for them around Luxor. Then, Polnareff senses someone following them and confronts the man.

Because of the power of Alessi's Stand, Set, Polnareff is turned back into a child. The one who came to his aid amidst his confusion was a woman named Marena. However, Alessi's evil hands followed Polnareff into her house.

After a long journey, Jotaro and the others finally reach Cairo. They go to a cafe and ask if anyone knows where DIO's mansion is located by showing the picture around. Then, someone says that they have seen the building before.

Souls are on the line as a game of poker continues.

Hol Horse arrives at Cairo in order to pursue Jotaro and the others. He has joined forces with another partner and is after the lives of Jotaro and crew once more. That partner, is none other than Boingo.

Hol Horse and Boingo followed Jotaro and the others to Cairo and as Boingo's book said, Hol Horse stuck his fingers into Polnareff's nose... but he didn't know what to do from there. Then Jotaro and the others, who were looking for Polnareff, show up, but things seem to be going the opposite way of the premonition.

Jojo and the others continue to look for DIO's mansion in Cairo. Following Abdul's advice, they have a beggar look for the mansion and wait. Meanwhile, Iggy, who is wandering the city alone, gets confronted by two large dogs. The dogs are freaked out by Iggy's power, and decide to go after a bird that's at a nearby mansion instead. However, as soon as the dogs go into the mansion, they are impaled by a giant icicle. Iggy is shocked by the occurance, and sees a falcon appear...

Iggy ends up in a battle to the death in the sewers against the falcon that guards DIO's mansion, Pet Shop. Pet Shop shows no mercy, and goes after Iggy at a frightening speed. Iggy, despite being injured, runs into the river, making a dome made out of dirt to shield him. However, he underestimates Pet Shop's abilities, and...

Despite Iggy's injuries, Jojo and company finally make it to DIO's mansion. Once they entered, a butler named D'Arby the Younger was awaiting their arrival. The younger brother of the defeated D'Arby the Elder, he immediately shows off his Stand, Atum's power.

The battle for souls with D'Arby continues. Kakyoin challenged D'Arby to a race game, but ends up losing and D'Arby steals his soul. Before Joseph really has time to react, Jotaro picks the next game.

The baseball match with D'Arby continues within DIO's mansion. For some reason, Jotaro starts declaring his pitches to D'Arby. D'Arby finds Jotaro's actions strange, but still believes he has the upperhand because of his Stand's abilities.

After a long, hard journey, they are faced with a sudden goodbye of a friend. Because it's so sudden, Polnareff can't control his emotions. He starts brandishing his sword toward the unseen enemy with very little success.

Polnareff is pushed to his limits with Vanilla Ice's merciless attacks. He finally awaits death, but is saved at the last minute by the dying Iggy. Iggy uses the last bit of his energy, but his Stand is obviously losing power. Polnareff then stabs Vanilla Ice in the head. Despite showing resilience to the attacks so far, Vanilla Ice is finally destroyed.

Polnareff encounters the Stand "The World".

The group tries to identify DIO's Stand.

The fight continues.

The final battle!

Florida, 2011. Framed for a DUI and imprisoned, young Jolyne gains a mysterious new power after receiving a bizarre item from her estranged father.

Jolyne gets acquainted with Green Dolphin Street Prison and her two-faced cellmate, Gwess, who has obtained Jolyne's locket and a pint-sized new Stand.

Jolyne acclimates to prison, but a mysterious boy delivers an ominous message before Jolyne receives a visit from her father and an enemy Stand user.

DIO's follower Johngalli A. aims for revenge. The boy risks his safety to help Jotaro and Jolyne, but she refuses to leave the kid behind.

Father and daughter try to escape the visiting room's trap and the prison, but an enemy Stand extracts two discs from Jotaro. One holds Star Platinum.

Jolyne returns to prison to retrieve Jotaro's discs. Ermes Costello discovers her new ability and a guard with discs in his head before she's attacked.

After people go missing from the prison's farm, Jolyne and Ermes volunteer to join the search party as a way to look for Pale Snake and the discs.

Jolyne and Ermes unravel the mystery of Stand F.F. and its user, who admits to helping Pale Snake in his efforts to steal their Stands.

Pale Snake's user, Father Pucchi, makes his entrance. A baseball game in the yard against Miraschon heats up when F.F. and Stone Ocean get involved.

Assisted by Emporio and his friend Weather Forecast, Jolyne rushes to the courtyard to pass Jotaro's Stand Disc to the Speedwagon Foundation.

Father Pucchi learns some damning information. Jolyne and Weather's bodies strain under Jumpin' Jack Spark's Stand ability as the fight continues.

Jolyne reaches the courtyard. Pucchi recalls his talks with DIO and his reason for hunting Jotaro when Weather unleashes a squall of poison dart frogs.

Realizing she hasn't seen Ermes for a few days, a curious Jolyne looks into her past and discovers that she came to the prison for a certain purpose.

F.F. and Jolyne try to assist Ermes in her fight against Sports Maximum, but they struggle against his Stand's ability to control the dead.

In a bid to find the bone, Jolyne intentionally gets sent to the Ultra Security House Unit. Hoping to save her, F.F. turns to Anastasia for help.

The Stand Survivor sparks brawls throughout the Disciplinary Wing. While fighting off a prison guard, Jolyne realizes that he is also a Stand User.

A victorious Jolyne looks out over the remaining prisoners. An old man approaches her and reveals he is a Stand User who has been sent by Pale Snake.

Jolyne notices that F.F. is becoming dangerously dehydrated in the fight against Kenzou and pleads with Anastasia to step in and help, but he refuses.

After Jolyne and her companions catch up to the man who has the bone, they notice strange plant growths emerging from the nearby fallen prisoners.

In a boat piloted by the obedient YA-YA MA, Jolyne and Anastasia flee through the wetlands. However, YA-YA MA attacks them with an invisible ability.

After realizing the connection between Father Pucchi and Pale Snake, F.F. defeats D an' G. As YA-YA MA disintegrates, the egg it swallowed hatches.

Weather Forecast summons some rain, which saves F.F. from the brink of destruction. They reunite with Jolyne and Anastasia, but the group gets attacked.

Jolyne resolves to escape Green Dolphin Island and put a stop to Father Pucchi's ambitions. A prison guard brings her a message from Pale Snake.

Guided by the words on her hand, Jolyne fights her fading memories, evades the prison guards and reaches the hidden room — just as Mew Mew planned.

With just five days until the new moon, Father Pucchi heads north and tries to stay ahead of Jolyne, but he is held hostage outside a hospital.

Splitting up with Weather Forecast, Anastasia tries to recover his physical body after the enemy Stand Bohemian Ecstatic separates it from his soul.

As Jolyne and her companions head toward Cape Canaveral in Romeo's helicopter, they are struck by something that forces their eyelids to close.

Jolyne learns a shocking truth about Weather Forecast after her fight with Rikiel. She and Ermes enter the hospital and find a hole dug in the floor.

Trapped by Versus's Stand in the memory of the crashed plane, Jolyne leaps from the aircraft and launches an attack, but it fails to affect Versus.

With Weather Forecast's memories restored, his powerful ability Heavy Forecast triggers automatically, turning everyone affected by it into snails.

Father Pucchi is born alongside his twin brother, who is switched with an ill-fated baby. As a young adult, he meets a strange man called DIO.

Jolyne's group hurries to find Weather Forecast and stop his Stand. Meanwhile, Weather Forecast resolves to settle the score with Father Pucchi.

With Weather Forecast's Stand disc in hand, Jolyne and her allies head to Cape Canaveral in pursuit of Father Pucchi, whose body begins to change.

Jolyne struggles against Father Pucchi's new Stand See Moon, a combination of Pale Snake and The Green Baby, which can invert anything it touches.

Although See Moon has inverted Jolyne, Father Pucchi senses that she is still alive and pursues her in hopes of ending the Joestar bloodline for good.

After shafts of bright light shine from Father Pucchi, Jolyne and her companions awake to find that he is gone and gravity has returned to normal.

Father Pucchi's new Stand Maiden Heaven overwhelms Jolyne's group with its sheer speed. Anastasia acts as bait while Jotaro prepares to attack.

The unstoppable acceleration of time brings the universe full circle. Emporio awakes in Green Dolphin Street Prison, and humanity enters a new world.