A day's worth of trauma takes its toll on the men and women of the ER. Dr. Greene looks into leaving the ER and joining private practice. Among other events, multiple casualties are brought in when a building collapses. New medical students report for duty, including Dr. Benton's new trainee, the young and inexperienced John Carter.

Dr. Lewis tries to get a mentally disturbed individual admitted to the psych ward. Carter has a difficult day, treating many members of wedding party, suffering from food poisoning. Dr. Ross finally visits Carol, eight weeks after her suicide attempt. Dr. Greene deals with an elderly gentleman having a difficult time letting go of his dying wife. He also discovers that Jenn passed the bar exam.

Carol returns after her eight week absence, finding Doug holding himself responsible. Carter finds himself watching over a mysterious, mentally ill singing woman. Susan clashes with Dr. Kayson over a diagnosis. Dr. Greene treats a domestic violence victim.

A business contractor with a bad heart gathers his family around him in the ER as he prepares for the end. Dr. Ross helps an asthmatic teenage girl when her mother doesn't have the funds. Carter worries that he may have contracted an STD from Liz. Dr. Lewis treats a teenager with alcohol poisoning. Jenn Greene prepares to move to Milwaukee.

The air conditioning quits on the hottest day in October which, coupled with closed ERs in Chicago's other two hospitals, leads to an extremely hectic day. Dr. Ross treats a six-year-old suffering from a cocaine overdose; Ivan Gregor, the liquor store owner, shoots and seriously wounds a young teenager. Susan's immature sister Chloe drops by, wreaking havoc in Susan's life. Doug picks up a pharmaceutical saleswoman, much to Carol's displeasure.

Morganstern invites Mark to join the staff as an attending physician. Mark treats an woman with breast cancer, who begs him to kill her. Deb "wows" Benton with her amazing presentation, leaving Carter in the rear again. Benton offends Haleh, who spends her day making his job extremely more difficult. The ER gets new crash carts, which are promptly stolen by cardiology.

Dr. Hicks berates Benton when he tries to switch shifts to attend his mother's birthday party. A teenage girl, a frequent patient of the ER, is brought in for a drug overdose. Carol decides she wants to adopt Tatiana while Tag isn't so sure. Dr. Ross slugs an abusive father in the lobby. Jen accepts a job offer in Milwaukee despite Mark's offer from Morganstern. Deb and Carter await the arrival of sub-internship applications.

Mark, still upset over the loss of Jodi O'Brien, takes the night off but ends up in the ER anyway, albeit an hour late, when the new chief runs a drill at 2:00 a.m. Benton begins to realize his mother's future is not bright. Carter and Deb compete against each other. A small moon coinciding with the naturally heavy Saturday night traffic causes an exciting night.

Deb and Carter compete furiously for procedures after Benton announces their books are due a week earlier than previously announced. Deb commits a nearly deadly error on a patient while trying to keep up with Carter. Doug's relationship with Diane Leeds grows. Peter and Jackie decide to put their mother in a home. Dr. Greene is put on trial, so to speak, in the M conference for Jodi O'Brien. Chloe returns.

Susan has her hands full with a pregnant Chloe. Benton goes to dinner with Jeanie. Greene further alienates Swift when he decides to honor a family commitment rather than stay longer at the ER to help him. Carter makes a good impression on Dr. Swift. Doug turns down an offer to "celebrate" with Linda Farrell, instead getting more serious with Diane as he agrees to coach Jake's Little League team.

Mark and Jennifer struggle to remain together as Mark has moved in with her in Milwaukee. Doug coaches Jake's little league team. Chloe's irresponsibility wears Susan down. Carter asks Benton to fill out a recommendation for the ER sub-I. Carol and Tag try to write their wedding vows; he becomes upset when Carol invites Diane Leeds, knowing that she'll bring Doug. Peter exhibits a growing attraction for Jeanie. Susan discovers what happened to Div when she spies his picture in a cabbie's dating service photo book. The staff discovers that Carter comes from a wealthy background.

Carter faces his last day in the hospital with aplomb, harshly grading Benton on an evaluation report. He later rescinds the report after finding out that the surgical sub-I is his. Carol faces wedding day jitters, culminating in Tag's deciding to call off the wedding. Chloe disappears again, abandoning little Susie with Susan. Dr. Swift changes his mind and decides to support Mark. Jake visits Doug.

Carol and Jeanie try to find a home for a schizophrenic architect. Carter signs Benton up for an interview with Vucelich for a prestigious study. Carter and Harper try to find a place to make out. Jenn and Rachel are involved in a car accident; Mark is thrown for a loop when he learns that Jenn has been having an affair with a coworker. Doug dines with his mother. Susan receives $3000 in the mail from Chloe.

Mark tries to find a way to tell Rachel about his impending divorce. Benton attends a banquet at Vucelich's home, with Jeanie as his date. Carter finally tells Mr. Rubadoux about his wife's terminal condition, making the man furious. Morganstern is admitted to the hospital after breaking a leg at a Scottish family reunion.

Mark and Kerry have to create a policy regarding HIV-positive employees, which leads to gossip amongst the nurses.

Benton goes into Carla's private hospital files when he fears that something may be wrong with their baby; Jeanie treats a suicidal woman who reveals a surprising secret; and Greene learns that Rachel has been lying about her health.

Benton tries to find out if everything's OK with Carla's baby. Carter tries to get a man operated, despite the fact Anspaugh thinks he will die no matter what.

Benton takes a day off to help Carla. Carter finds out Edson falsified a chart.

Anspaugh is furious when Carter tells him he wants to quit surgery. Charlie is brought in with an overdose. Mark keeps struggling with his beating.

Jeanie believes she's been fired because she has HIV and fights her dismissal.

Third-year med student Lucy Knight reports to the ER for the first day of her rotation. Greene takes a teacherly interest in her, helping her get acquainted, but she gets off to a bad start with the irritable Carter when she speaks insensitively, and without Carter present, with a patient's wife about her husband's very serious condition. The rest of the day finds her comforting a woman who has suffered a miscarriage, getting locked out on the roof, having Carol bail her out on a simple procedure, and trying to figure out Kerry Weaver's "Tour on Tape."

Dr. Corday's father visits from overseas in an attempt to convince her to join his medical practice. Weaver suggests that Elizabeth look into alternative methods to stay in America, like starting over as an intern. Weaver also doesn't let an opportunity pass to remind Doug of the way he bypassed her authority in the McLean case. Lucy continues learning, earning more of Carter's respect than she deserves. Peter takes Reese in for another hearing test. Mark has several discussions with paramedics about the state of the EMT program. Carol hires a nurse practitioner to help out in the clinic. Carter is having trouble being an RA in the dorms.

Mark goes to a trauma scene with the EMTs, where he treats a gunshot victim who has a bomb strapped to himself. Later, Mark’s daughter persuades him to treat a horse with colic, and Jerry gets the bad end of the enema. Carter intubates an elderly woman who is DNR. When her HMO declines to admit her, Carter either has to find a relative quickly or let her die. Kerry finds herself more and more frustrated when Anspaugh suggests that they're not considering her for ER Chief, and she discovers she’s the last to hear that Doug was made a pediatric attending. Corday serves her last day as a surgical fellow. Benton meets with Carla to discuss getting Reese hearing aids. Jeanie returns from vacation. Carter goes out with Roxanne, the insurance saleswoman he treated.

Halloween night finds the ER awash with allergic or otherwise incapacitated children. Kerry tolerates a visiting candidate for chief while she waits for the official vote. Romano operates on an 11-year-old girl and finds she's genetically male. Carter leaves Lucy in charge of a dorm party he's supposed to be overseeing, with unfortunate results. Mark learns that Jenn's moving to St. Louis--with Rachel. Mark and Carol treat a pregnant schizophrenic.

After his mother's funeral, Dr. Greene comforts his father in San Diego. In Chicago, Romano surprises Corday by appointing her associate chief of surgery. Corday treats Elaine, Carter's lover, for breast cancer.

On Thanksgiving Day Carol goes into labor. She's able to get to the ER only thanks to Luka's help. She delivers the first baby in the ER, but the second causes some trouble. Greene leaves Elizabeth to deal with his father and daughter, as he rushes to assist Carol.

Greene prepares to bury his father. Chen worries about Carter's mood swings. After witnessing the interaction between a dying woman and her family, Hathaway realizes she wants her family together and flies to Seattle to join Ross.