Dr. Carter, Abby and other staff of the ER are quarantined as the CDC investigate a mysterious, deadly outbreak.

After another hospital shuts down, the ER is flooded with patients. Dr. Pratt resuscitates a heart-attack victim who had been pronounced dead.

Dr. Carter leads a walk-out of staff protesting lack of security in the ER.

Weaver makes a mistake on live television while demonstrating flu shots, inadvertently sticking two reporters with the same needle. In the bathroom later, Susan and Abby catch Weaver in a stall with a needle. Weaver confesses to Susan that she's taking hormones. Carter, assuming Susan knows already, tells her about Abby's drinking problem. Abby becomes nurse manager, and argues with Carter about her drinking. Luka flirts with a patient's mom and is caught emerging from a storage closet with her. Gallant has a rough day: Pratt butts in on a patient of his, and Stella Willis dies because Kayson didn't bother with thorough treatment.

On a busy Halloween night, Carter and Abby are the only staffers in costume when victims of an apartment building fire pack the ER. Corday takes on a new med student for a surgical rotation - Paul Nathan, who suffers from Parkinson's disease and decided to pursue medicine after being diagnosed. Despite a difficult first day, both professionally and medically, Nathan makes a difficult diagnosis. Romano's rehab lags behind his expectations, and he begins to doubt his role in surgery is no longer an option.

Corday clashes with new surgical resident Paul Nathan regarding his intervention into the treatment of a sickly young woman, Alison, who has signed a "do not resuscitate" order. Abby wonders about the erratic behavior of her visiting brother Eric, and feels conflicted over a nurse's official complaint against Kovac, Abby's former lover. Meanwhile, Pratt comforts Chen after a patient threatens her, and Corday suspects that an unconscious, 14-year-old female patient has been sexually assaulted.

Abby fears the worst when her brother Eric suddenly disappears. Carter and Chen treat a frightened Chinese immigrant nanny, Tong-Yi, whom they suspect was impregnated by her employer. Meanwhile, new surgical resident Paul Nathan, who is struggling to overcome a physical disability, tries to help in the emergency room—but his fellow doctors do not appreciate his advice to patients. Unable to quench his sexual appetites, Kovac also gets into trouble in his professional life, despite his admirable resolve to find an eye specialist to treat a young gunshot victim. Gallant and fellow medical student Erin Harkins engage in an escalating competition of medical knowledge. And Weaver gets some much-needed good news.

Abby's family nightmare continues as she and her mother Maggie search for Abby's missing brother Eric, who Abby suspects is suffering from serious mental problems. Meanwhile, Corday treats a family of patients who, while building a snowman, were severely injured after being struck by a truck driver.

Abby is distressed when her mother interferes with Eric's treatment at a psychiatric hospital. Pratt treats a frightened young girl who has been injured in an auto accident and desperately wants to hide a secret. An unhappy Luka forms an unlikely bond with a lonely elderly woman who makes him a surprising offer. Chen is overcome with upsetting memories when a baby is abandoned in the emergency room. Pratt takes action after Leon is fired from his menial job.

Dr. Kovac's speeding causes a crash on an icy road. The ER staff treats angry elves and a female hockey player with a head injury.

Dr. Pratt brings a gun into the ER; Dr. Weaver tries to conceal her pregnancy; a woman plots against her dying husband; Dr. Chen treats math students who overdosed on an unknown stimulant.

Dr. Weaver is in a difficult situation when an alderman tests positive for syphilis. Dr. Carter is impressed when he meets a man who runs an inner city clinic.

Dr. Pratt's disabled roommate leads him to a wounded thief. Dr Carter decides to practice medicine in Africa. A doctor makes a pass at Dr. Corday.

Abby's troubled brother is missing. A car runs into a crowd of teen girls. The alderman with syphilis gives Dr. Weaver a promotion. Dr. Lewis looks forward to a blind date.

Abby comes close to breaking down trying to deal with her mother. Dr. Pratt goes for his required paramedic ride-along. Dr. Weaver confronts the man who stole her purse. Dr. Lewis has a teen admirer.

The police question Drs. Pratt and Gallant about a rampage at the diner across from the ER. Dr. Lewis befriends her teen admirer, a cancer patient.

Dr. Weaver bends the rules and treats the Alderman's lover for syphilis. Dr. Kovac's patient claims she was sexually abused at a boot camp for troubled youth. Dr. Carter treats a women with a nasty personality.

Dr. Romano seizes control of the ER and manages to offend everyone. Dr. Kovac asks Dr. Corday's help in the quest to bring a sickly Croatian boy to the U.S. for medical treatment.

A psychotic patient threatens Abby. Dr. Weaver suspects a woman poisoned her own baby. Dr. Romano continues to make rash judgments.

Dr. Carter tries to prevent a grieving gang member from going after vengeance. Dr. Kovac races against time to save a Croatian boy's life. A baseball player gets treatment for a heart problem.

Carter's day shift and Pratt's night shift (his final shift at County) are intercut. Both men have extremely busy days. Doc Magoo's burns down. Luka calls Carter from the Congo and asks for help. Carter decides to go. Pratt decides to stay at County. In other parts of the hospital, Romano has his now-useless left arm amputated.

Carter travels to the Congo after Luka calls and asks for help. During the course of his two weeks there, he learns how much different the conditions are against what he's used to. Luka decides to stay for a while as Carter heads back to Chicago, ending up at a sleeping Abby's bedside.

Carter returns from Africa, going straight to Abby's bedside. Her response to seeing him is to ask for her key back. She is very chilly towards him all day until new med student Neela Rasgotra answers a phone call for Carter. The message: Luka is dead. Carter decides to go back to the Congo to bring the body back. Neela has a tough first day in the ER, earning Chen's ire after Pratt flirts with her. Gallant, now a full-fledged doctor, helps to show her the ropes.

John Carter returns to the Congo to retrieve Luka Kovac's body. He finds however that the area where was killed is still too dangerous to enter. He and Gillian finally manage to hitch a ride with a Red Cross worker, Debbie, who is going to the area. In flashbacks, we learn how Kovac and his fellow aid workers were taken prisoner by rebel troops. They are shot, one at a time, until only Luka is left. Amid the destruction of the eastern Congo, we learn his fate. Carter also makes a fateful decision.

Luka Kovac arrives safely at County General and is hospitalized for treatment. His friend Gillian delivers John Carter's letter to Abby.

Confident second-year resident Pratt wants to prove his abilities when he works the graveyard shift (11 p.m. to 7 a.m.), but his heroics sometimes backfire. Pratt shows contempt for a man, Ed Gamble, who presents no symptoms of disease but temporarily loses his speech.

Ben Hollander is a distraught architect whose degenerating eyesight causes him despondent while a spirited new nurse, Samantha Taggart joins the staff. Elsewhere, disaster strikes when the doctors suspect a mother is abusing her child while Dr. Corday learns something shocking about the charismatic Dr. Dorset, and Dr. Archie Morris is overwhelmed by the chaos and grisly conditions of life in the E.R.

Pratt and Kovac clash over a miscarriage-prone young woman, Denny, who arrives to deliver a premature baby. Pratt wants to make heroic efforts to save the unborn child, while Kovac is adamantly against spending vast amounts of money to keep the forever sickly baby alive.

To everyone's amazement, Lewis makes a date to share a home-cooked dinner with the elderly Ben Hollander, her depressed patient who is going blind.

On Thanksgiving Day, a helicopter crash outside the ER leaves several injured, and kills Dr. Romano. Alex tries to bring Sam and Luka together.

Neela helps treat two Amish teens who were in a car crash. Sam argues with Dr. Kovac when he pays too much attention to her son.

Dr. Carter celebrates Christmas at a clinic in the Congo dealing with low supplies and anti-Americanism, but in the meantime, falling for an AIDS worker named Makemba.

Carter returns to County General to hearty welcomes. Although Abby is shocked to learn that Carter's beautiful African girlfriend, Kem, is already pregnant with Carter's child, Abby has moved on with her life as well, going back to medical school.

Abby and Neela are assigned to a month-long rotation in the neonatal intensive care unit where they experience emotional roller coasters while caring for the sick infants.

Dr. Carter's girlfriend makes an impression as she observes ER operations. Dr. Gallant is almost shot during a domestic incident. Dr. Weaver dedicates a center to the memory of Dr. Romano.

Sam treats an abused, pregnant teen. Dr. Carter introduces African girlfriend Makemba to wintertime. ER chaos shocks a risk-assessment expert. Dr. Pratt and Abby restrain a man who has tuberculosis.

Carter misses his pregnant girlfriend who has returned to Africa. A family of four is rushed to the emergency room after suffering carbon monoxide poisoning from their faulty furnace--forcing the claustrophobic Neela to accompany a newborn baby into an extremely uncomfortable hyperbaric chamber.

Morris streets a patient without getting a psych consult, and the guy steals a tank and heads for County. Gillian is visiting Luka, and Sam's not happy about it. Luka and Sam make up by the end of the day though. A 13-year-old boy has chlamydia. Frank has a heart attack. Corday plays the dating game, going out with two men.

Carter sticks up for Neela when the other attendings doubt her future in the ER. Neela caves to the pressure and accidentally gives a patient the wrong medication. Gallant takes the blame for her though. Sam and Luka try to plan Alex's birthday party. Frank visits on his way to therapy. Chen's home nurse quits after her dad behaves poorly.

Weaver rushes to the aid of her female life partner, Sandy Lopez, when the firefighter is severely injured while working and must now battle for her life. Frightened Weaver whispers hope to Sandy by reminding the victim of their newborn child.

Pratt struggles to diagnose a woman who suffers mysterious chronic seizures. An attractive woman, Campbell, informally accuses flirtatious Pratt of sexual harassment. Abby ponders how to get her contentious patients' attention during her psychiatric department rotation.

A panic-stricken Weaver is ordered to give her son to the Lopez family. Carter greets the returning Kem, but their meeting with his father, Jack, gets tense after Carter announces plans for his grandmother's estate.

Carter takes Kem to the hospital to check on their baby since it's not kicking anymore.

Kovacs stops to help a woman and her son whose car broke down. Steve is getting close to Alex, and Sam panics. Abby is looking for her letter whether to see she passed her boards. Pratt shows off his new Chrysler. Elgin tries to build a connection between him and Pratt. Jing-Mei might be battered by her senile father.

Season Premiere. Moretti's first day is challenging as the ER is inundated with casualties from the peace rally - including Neela. Dubenko faces a crisis in surgery. Abby, Pratt and Morris conspire about how to deal with a shared problem. A new intern arrives unexpectedly, and Gates is reassigned.

Moretti begins to make his presence felt, as he implements changes in the way patients are seen. The ER staff differ on how procedure when a patient comes in with a bullet in him needed as evidence. Neela finds herself the object of more attention that she wants, or needs. Abby had passport woes, and struggles with the changes being made. Pratt and Morris find themselves forced to defend their actions, Hope prepares for a new mission, and Gates finds himself labeled the reject in his new assignment.

Two wounded police auxiliary officers present challenges in the ER. Neela settles in with Abby as she recovers, while Pratt and Bettina consider their relationship. Gates tries to get a patient on a drug trial, with Dubenko's help. And Morris is in a funk that not even a pretty woman can help.

When Baby Joe is injured by a fall at the playground and rushed to the hospital, Abby is unable to reach Luka to tell him.

Moretti reassigns Gates back to the ER and treats a couple involved in a car accident. Morris prepares to take his written board exams. Neela is assigned a young genius intern. Kovac plans to extend his stay in Croatia while Abby struggles with single parenthood.

Morris and Pratt cram for their medical boards when Morretti brings in a new attending physician to help with the load. Sam and Abby work on an attention-hungry patient who comes into the ER with elusive symptoms.

A power outage strikes on an unusually hot day, bringing nursing home patients suffering from hyperthermia to the ER. Abby and Pratt disagree about diagnostic tests for a fussy baby. Morris and Pratt get their board results, and the ER staff celebrates at Ike's. Moretti and Abby's interactions intensify, and Abby finds herself at a dark and frightening crossroads.

Everyone at the ER is happily surprised to see Luka back from Croatia. Great news awaits Neela. Sarah once again needs rescuing by Tony, and patients are causing problems for Morris.

It's time for changes at the ER when Anspaugh makes an unpopular decision. Abby has old demons to fight with, which distance her from friends and family. Even Luka seems to be at a loss to help Abby. Love is in the air when a secret romance blooms between two doctors.

ER's 300th episode finds Luka and Abby hurriedly preparing to travel to Croatia after Luka's father passes away. Luka confronts Abby about the estrangement between them, and she eventually reaches out and asks for his help. A man rushes to the ER when his wife is seriously injured in a car accident, and finds someone very unexpected there with her. Julia holds a service to bless the ER and remember the patients that have been lost through the years.

After being passed over for Chief of the ER, Pratt is looking for a hospital that will appreciate his talents. A former employee of the ER brings her sick son in for tests. Neela's cousin is in town for a visit, and Morris and Harold compete for her affections.

Abby is back from rehab and finds herself the object of scrutiny. She confesses to Pratt that Luka might stay in Croatia longer than planned. Harold seems to have won over Neela's cousin. Multiple victims from a fire fill the ER.

Neela's short visit in Ortho turns into a game of hockey. Bettina wants to take her relationship with Pratt to the next level, but Pratt is not keen on the idea. Gates and Sam disagree over a patient. Julia provides some spiritual guidance in order to ease a prison doctor's bad conscience.

Pratt and a new doctor on the scene disagree on how to teach the interns. Gates treats a young woman with serious heart problems. Abby heads to Croatia, and ponders whether and how to tell Luka about her unfortunate choices. Sam discovers that Julia has moved on in more ways than one.

Neela, worn out after being on shift for over 24 hours, has to make a quick decision regarding an accident victim's torn aorta. Sarah's grandparents are in town, and Hank is rushed to the ER after collapsing during an outing. Gates tries to convey to Sam that his feelings for her are serious.

Kovac is in Chicago looking for hospice-care work. Neela's aorta surgery has caused an infection in her patient. Abby treats a teen who has been beaten up. Brenner continues to cause problems for the ER staff.

There's been a jewelry robbery in town, and Neela finds out that one of her patients might have had something to do with it. Pratt makes an effort to save his relationship with Bettina, and Abby worries about her marriage, sensing that Luka may have given up on it.

Neela's aortic rupture patient is in need of yet another follow up surgery, and they are starting to take a toll on her. Morris talks with a shrink about his experience with the jewelery thieves. Abby needs to make a tough decision when a new opportunity is presented to her.

When a drunk patient is admitted to the ER, his actions endanger everyone at County. Pratt is still pursuing his dreams of becoming Chief of the ER, and Gates is worried about his future with Sam. Luka unexpectedly runs into Dr. Moretti.

The 15th and final season of ER begins with the devastating repercussions of the ambulance explosion. As Morris and Neela do everything they can to save a wounded colleague, Abby treats a young girl injured during the blast.

Everyone in the ER is trying to cope with the loss of their colleague. The staff feels defensive toward the new Chief and her tough disposition. Gates and the new interns treat a bio terrorist who has a lethal secret that endangers them all. Neela makes a great effort to get Dubenko back on the surgery staff, and gets help from an unexpected source.

Abby's first day as an attending is bittersweet. Neela is hurt when she finds out Abby's news from someone else. Abby and the new ER Chief argue over how to treat a gunshot victim. Abby comes to Sam's aid when she faces a nurses' disciplinary board.

Dr. Banfield defends herself during a mugging. Dubenko returns to work, due in no small part to Brenner's organized protests. A young gymnast comes into the ER with injuries consistent with a fall, but Banfield and Gates each think a different family member may actually be to blame. Sarah neglects to ask Gates's permission before getting her tongue pierced.

It's Halloween night, and the interns continue to be paired with the residents. Gates's teaching methods with Daria, and her responses, belittle Sam. A school fight results in a stabbing and a nose that won't stop bleeding, with Brenner treating the victims and being deeply affected by the truth behind their confrontation. The staff, especially Neela, are enthusiastic about a surprise visitor. Gates gets locked in a maintenance area with a quiet young boy.

Chaz, now a med student, begins his ER rotation. Morris takes him under his wing and shows him some risky procedures, endangering a patient and raising Banfield's ire. Neela becomes upset when Banfield questions her authority and skills in front of her intern. Gates invites Sam and Alex to move in with him and Sarah.

While out for a mind-clearing run, Banfield encounters a desperate situation and finds herself trying to rescue a young girl from drowning in a nearby lake. Painful memories of her son in mortal danger and Dr. Greene's heroic attempts to save him are triggered during the experience. Meanwhile, Gates attempts to pull some strings to help out a homeless war veteran, and the interns continue to struggle in the ER.

Sam gets frustrated with Gates when he gets obsessed with finding a homeless war hero. Neela is upset at her intern after he gets the entire surgery department into a lawsuit. A husband and wife come into the ER after someone tried to burn down their home. Brenner loses his cool with a patient and it gets physical.

As a snowstorm hits Chicago, Sam's son Alex crashes a car and ends up in critical condition in the ER. Neela gives a deposition in the malpractice suit against her. Banfield and Morris are both at a medical conference in Omaha, and when the snow cancels all flights out, they share a memorable and surprising evening.

A package for Morris from his deceased father is delivered to the ER. Sam has some anxiety over Alex being removed from the ventilator. A woman with a high-risk pregnancy worries that she will be deported. An old friend returns to celebrate the holidays.

When a drug deal goes bad, two brothers sustain serious injuries and are brought to the ER. Tensions continue between Gates and Sam, coming to a head when Tony is the last to know Alex is about to be released from the hospital. Neela has to tell a young girl with sickle cell anemia that she must have an operation, and the case leads her to consider specializing in pediatric surgery. A feisty patient takes Morris into her confidence. Banfield ponders her choices about expanding her family.

Neela has recurring dreams about trying to save a girl with sickle cell anemia. In them, she also goes to an attending interview and sees an old colleague, has conversations with Ray, welcomes Brenner back from Australia, and assists Gates and Banfield in trying to save a "dream runner" who jumped out of a window during his sleep.

Morris faces a complicated case involving a young girl hit while riding her bicycle. Gates finds it very difficult to let go of his feelings for Sam. Neela becomes quite flustered when Brenner returns from Australia.

Gates and Morris tend to an elderly man who was assaulted on the street. Sam 's sister shows up unexpectedly. Brenner and Dubenko clash while treating a mother thought to have late-stage cancer. Dr. Morgenstern returns to the ER to assist a former mentor who is seriously ill.

A car accident in the ambulance bay injures a woman with a young child and leaves the mother in need of surgery with a significant recovery time. Brenner has difficulty finding a family member to care for the daughter. Gates treats an elderly patient who refuses treatment because he's afraid his condition will prolong an inevitable death. Morris impresses Claudia and her family. Neela tells Brenner about her job offer from North Carolina.

It's Valentine's Day. Dr. John Carter is back at the County. Brenner and Neela are getting closer. Dr. Banfield is having a hard time trying to have a baby. And Puck and mushrooms may not be a good combination.

Carter finds himself struggling with County's new technology and procedures. After becoming frustrated with the in vitro-fertilization, Banfield and her husband discuss adoption as an option. Sam's mother arrives in an altered state of mind.

A camera crew shooting footage for a documentary interviews members of the ER staff. Detective Claudia Diaz is brought in, critically injured with gunshot wounds. Neela laments the lack of communication between her and Brenner. Sam struggles to reconcile with her mother. Carter's condition worsens quite suddenly.

Neela and Sam are shocked when they arrive back to the airport with transplant organs only to find that their plane has left them. Dr. Carter gets a surprise visit from an old friend while waiting for his kidney transplant. Dr. Banfield bonds with an abandoned baby boy that is left at the ER.

On Neela's last day at County, she has doubts as to whether she is making the right decision.

The ER doctors and nurses help out at Camp Del Corazon, a camp for kids who have had open-heart surgery, working alongside the camp counselor.

As Carter prepares to open a new facility for the underprivileged, some old friends/colleagues gather. Rachel Greene, Mark Greene's daughter, applies for an internship at County.