Donald Anspaugh has a new method to increase the staff's efficiency, new intern Maggie Doyle joins the ER and Susan asks Mark to come along to Hawaii.

Mark and Kerry have to create a policy regarding HIV-positive employees, which leads to gossip amongst the nurses.

Mark finds out Cynthia has moved. Carter's cousin Chase is brought in because of a heroin overdose. Doug and Kerry clash after she found a flaw in his study.

Del Amico, Ross and Corday confront disturbing situations after the bombing of a women's clinic. Benton comes under review for controversial actions in the OR. Jeanie endures one of the most difficult days of her life as she says goodbye to a friend.

Doug faces possible criminal charges after Ricky Abbott dies when Ross bypasses system lockouts to enable Joi to give Ricky a lethal dosage of dilaudin. Doug is delegated to desk duty, Carol's clinic is shut down for acquiring the P.C.A. machine for Ricky, and Greene and Weaver face future disciplinary action for not reporting Doug's tampering with the double blind study. Carter and Lucy discover a mutual attraction. Benton studies with a sign language instructor.

Greene assists paramedics in treating injured children at a school bus accident. En route, Doug and Jeanie survive their own accident. Kerry stops Doug from treating Jeanie...or any other patient. Doug decides to resign and leave Chicago for the Northwest and asks Carol to come with him. She decides against it, but he leaves anyway. Carol steps down from running the clinic so that Anspaugh will keep it open. Jeanie discovers she may have contracted hepatitis. Hospital janitor Mobalage's wife is stabbed.