Greene assists paramedics in treating injured children at a school bus accident. En route, Doug and Jeanie survive their own accident. Kerry stops Doug from treating Jeanie...or any other patient. Doug decides to resign and leave Chicago for the Northwest and asks Carol to come with him. She decides against it, but he leaves anyway. Carol steps down from running the clinic so that Anspaugh will keep it open. Jeanie discovers she may have contracted hepatitis. Hospital janitor Mobalage's wife is stabbed.

After his mother's funeral, Dr. Greene comforts his father in San Diego. In Chicago, Romano surprises Corday by appointing her associate chief of surgery. Corday treats Elaine, Carter's lover, for breast cancer.

Benton struggles with the idea of taking a DNA test to determine whether or not Reese is actually his son. As the signs continue to pile up, Kerry and Mark use a fake patient to convince Dr. Lawrence of his Alzheimer's. Carter has trouble persuading a woman from a nursing home fire to sign a DNR for her husband and later is asked to forge charts for a family with no insurance. Carol continues to meddle in Meg's life, having her arrested so that she can be detoxed. Cleo is blamed for an explosion in the suture room but it may actually be Dr. Dave's fault.

Weaver tries to save the life of a rape victim while Corday struggles with feelings of disdain as she is forced to save the rapist. Cleo treats a teenage alcoholic boy whose alcoholic mother refuses to recognize her problem or his.

As the result of a school shooting, Kovac and Benton care for the gunman and his victims. Abby discovers that Carter has been illegally injecting pain relievers. Greene and Weaver confront Carter about his problem, and Weaver orders him to enter a drug rehabilitation center or leave the hospital permanently.

Dr. Carter struggles with his drug dependency; a custodial strike leaves the ER cluttered with garbage; a riot at a high-school football game leaves several wounded.

Dr. Carter is allowed a cautious restart with small steps. An extremely blond Dr. Malucci is very curious who's made Dr. Chen pregnant. Dr. Benton has been written out of all the hospital's systems and is stunned by Dr. Romano. An unfortunate incident at a Science Fiction convention makes it look like scenes from the movie 'Mars Attacks'.

Benton and Cleo clash over his deceased nephew's girlfriend. They finally agree to call a social worker. Benton confesses his love to Cleo. The spinal surgery malpractice suit is settled by employing a technicality: the equipment used was later recalled by the manufacturer. But Corday now doubts her abilities as a surgeon.

Greene returns to work but confuses words and displays uncharacteristic anger. Eager to get out of his per diem situation, Benton agrees to a full time position. Carter visits his cousin, who became paralyzed after a drug overdose. A workplace disaster results in numerous injuries and fatalities among illegal immigrants.

In the series' 150th episode, a massive train wreck mobilizes the emergency room doctors. Corday, Carter and Kovac rush to the scene. Corday falls and injures her back, bringing on contractions in only her 25th week of pregnancy. While amputating the legs of a fallen firefighter, Corday stops because of her pain.

Weaver fears for her own reputation when Legaspi is accused of sexual harassment. Afraid to reveal her relationship with Legaspi--for both personal and professional reasons--Weaver fails to support her during the investigation. An infant is abducted from the hospital and later found on a train platform.

Numerous mishaps threaten to mar Corday and Greene's wedding day. As the very pregnant Corday becomes increasingly agitated, the presence of her bickering divorced parents does little to improve her mood. With the intense rain, Greene has a difficult time making it to the church. But, evenutally, he arrives and they joyfully wed.

Cleo and Carla clash after Reese gets hurt while in Cleo's care. Weaver and Kovac cannot save the life of a developmentally challenged woman's only caregiver. Abby goes to a therapy session with Maggie. Later, Abby confesses to Maggie that she is afraid to bear children because they might be bipolar like her mother.

The ER is flooded with foster care home residents, attacked by a shooter bent on tracking down his son, who , with the help of Dr. Green, was put into the foster care system amid allegations he was being abused by his father.

Carter is overwhelmed by patients from a rock concert riot. Benton's former girlfriend is killed in a car accident. Newly promoted to chief resident, Chen panics and misdiagnoses a patient. Kovac angers Abby by flirting with a waitress.

Greene's daughter comes to live with him and Corday. Carter and Abby become more intimate. Chen must prove her skills while saving a baby. Weaver terminates Malucci after witnessing him having sex in an ambulance.

Dr. Susan Lewis arrives, looking for work in the Chicago area again. Greene hires her, over Weaver's objection. Chen nervously attends a risk management review, accompanied by the unforgiving Weaver, to discuss a patient who recently died under Chen's supervision.

An injured and condemned murderer wants to die in the ER rather than await execution; Abby advises a neighbor to seek shelter from her abusive husband.

An accidental overdose brings Drs. Green and Corday's baby into the ER.

As Dr. Greene's brain tumor begins affecting his coordination, he becomes concerned that his fate will be similar to the terminally ill patients he treats.

Just when the ER is understaffed and swamped, two children who were brought in turn out to have full blown smallpox. The entire ER must be locked down. The staff needs to improvise while they battle not only the disease but also frayed tempers.

After another hospital shuts down, the ER is flooded with patients. Dr. Pratt resuscitates a heart-attack victim who had been pronounced dead.

Weaver makes a mistake on live television while demonstrating flu shots, inadvertently sticking two reporters with the same needle. In the bathroom later, Susan and Abby catch Weaver in a stall with a needle. Weaver confesses to Susan that she's taking hormones. Carter, assuming Susan knows already, tells her about Abby's drinking problem. Abby becomes nurse manager, and argues with Carter about her drinking. Luka flirts with a patient's mom and is caught emerging from a storage closet with her. Gallant has a rough day: Pratt butts in on a patient of his, and Stella Willis dies because Kayson didn't bother with thorough treatment.

On a busy Halloween night, Carter and Abby are the only staffers in costume when victims of an apartment building fire pack the ER. Corday takes on a new med student for a surgical rotation - Paul Nathan, who suffers from Parkinson's disease and decided to pursue medicine after being diagnosed. Despite a difficult first day, both professionally and medically, Nathan makes a difficult diagnosis. Romano's rehab lags behind his expectations, and he begins to doubt his role in surgery is no longer an option.

Abby fears the worst when her brother Eric suddenly disappears. Carter and Chen treat a frightened Chinese immigrant nanny, Tong-Yi, whom they suspect was impregnated by her employer. Meanwhile, new surgical resident Paul Nathan, who is struggling to overcome a physical disability, tries to help in the emergency room—but his fellow doctors do not appreciate his advice to patients. Unable to quench his sexual appetites, Kovac also gets into trouble in his professional life, despite his admirable resolve to find an eye specialist to treat a young gunshot victim. Gallant and fellow medical student Erin Harkins engage in an escalating competition of medical knowledge. And Weaver gets some much-needed good news.

Abby is distressed when her mother interferes with Eric's treatment at a psychiatric hospital. Pratt treats a frightened young girl who has been injured in an auto accident and desperately wants to hide a secret. An unhappy Luka forms an unlikely bond with a lonely elderly woman who makes him a surprising offer. Chen is overcome with upsetting memories when a baby is abandoned in the emergency room. Pratt takes action after Leon is fired from his menial job.

Dr. Pratt brings a gun into the ER; Dr. Weaver tries to conceal her pregnancy; a woman plots against her dying husband; Dr. Chen treats math students who overdosed on an unknown stimulant.

Dr. Weaver is in a difficult situation when an alderman tests positive for syphilis. Dr. Carter is impressed when he meets a man who runs an inner city clinic.

Dr. Pratt's disabled roommate leads him to a wounded thief. Dr Carter decides to practice medicine in Africa. A doctor makes a pass at Dr. Corday.

Abby's troubled brother is missing. A car runs into a crowd of teen girls. The alderman with syphilis gives Dr. Weaver a promotion. Dr. Lewis looks forward to a blind date.

Abby comes close to breaking down trying to deal with her mother. Dr. Pratt goes for his required paramedic ride-along. Dr. Weaver confronts the man who stole her purse. Dr. Lewis has a teen admirer.

The police question Drs. Pratt and Gallant about a rampage at the diner across from the ER. Dr. Lewis befriends her teen admirer, a cancer patient.

Dr. Weaver bends the rules and treats the Alderman's lover for syphilis. Dr. Kovac's patient claims she was sexually abused at a boot camp for troubled youth. Dr. Carter treats a women with a nasty personality.

Dr. Romano seizes control of the ER and manages to offend everyone. Dr. Kovac asks Dr. Corday's help in the quest to bring a sickly Croatian boy to the U.S. for medical treatment.

Carter's day shift and Pratt's night shift (his final shift at County) are intercut. Both men have extremely busy days. Doc Magoo's burns down. Luka calls Carter from the Congo and asks for help. Carter decides to go. Pratt decides to stay at County. In other parts of the hospital, Romano has his now-useless left arm amputated.

Carter returns from Africa, going straight to Abby's bedside. Her response to seeing him is to ask for her key back. She is very chilly towards him all day until new med student Neela Rasgotra answers a phone call for Carter. The message: Luka is dead. Carter decides to go back to the Congo to bring the body back. Neela has a tough first day in the ER, earning Chen's ire after Pratt flirts with her. Gallant, now a full-fledged doctor, helps to show her the ropes.

Confident second-year resident Pratt wants to prove his abilities when he works the graveyard shift (11 p.m. to 7 a.m.), but his heroics sometimes backfire. Pratt shows contempt for a man, Ed Gamble, who presents no symptoms of disease but temporarily loses his speech.

Ben Hollander is a distraught architect whose degenerating eyesight causes him despondent while a spirited new nurse, Samantha Taggart joins the staff. Elsewhere, disaster strikes when the doctors suspect a mother is abusing her child while Dr. Corday learns something shocking about the charismatic Dr. Dorset, and Dr. Archie Morris is overwhelmed by the chaos and grisly conditions of life in the E.R.

Pratt and Kovac clash over a miscarriage-prone young woman, Denny, who arrives to deliver a premature baby. Pratt wants to make heroic efforts to save the unborn child, while Kovac is adamantly against spending vast amounts of money to keep the forever sickly baby alive.

Neela helps treat two Amish teens who were in a car crash. Sam argues with Dr. Kovac when he pays too much attention to her son.

Carter returns to County General to hearty welcomes. Although Abby is shocked to learn that Carter's beautiful African girlfriend, Kem, is already pregnant with Carter's child, Abby has moved on with her life as well, going back to medical school.

Carter misses his pregnant girlfriend who has returned to Africa. A family of four is rushed to the emergency room after suffering carbon monoxide poisoning from their faulty furnace--forcing the claustrophobic Neela to accompany a newborn baby into an extremely uncomfortable hyperbaric chamber.

Morris streets a patient without getting a psych consult, and the guy steals a tank and heads for County. Gillian is visiting Luka, and Sam's not happy about it. Luka and Sam make up by the end of the day though. A 13-year-old boy has chlamydia. Frank has a heart attack. Corday plays the dating game, going out with two men.

Kovacs stops to help a woman and her son whose car broke down. Steve is getting close to Alex, and Sam panics. Abby is looking for her letter whether to see she passed her boards. Pratt shows off his new Chrysler. Elgin tries to build a connection between him and Pratt. Jing-Mei might be battered by her senile father.

Neela starts a new job in the emergency room after working at the convenience store near the hospital. On Neela's first day, Pratt expects the interns, Abby, Ray and Neela, to take on a large patient load during their shifts. Pratt turns processing the patients into a competition, in which Ray is clearly going to be the winner.

A rape victim, barely able to speak, does all she can to help police find her attacker.

A soccer mom finds herself completely aware of everything going on around her, but is unable to move or speak after suffering a stroke.

Morris is named the new chief resident, which makes nobody really happy, except Morris. Meanwhile Luka and Sam are having communication problems, Carter gets a promotion Susan really wanted and Ray finds out a 14-year old who always comes in for free drugs has been raped.

The rainy night brings in diverse patients including a mother involved in a car accident with her baby, a man with a satisfaction facilitator, and a comatose patient who suddenly wakes up. Also, Sam steps up to Eve and her strict ways and Jerry gets struck by lightening!

The ER prepares to take in victims from a plane collision, while Neela and Pratt head out to the crash site where Neela makes heroic efforts. At the end of the day, Neela gets a surprising visit.