When a Marine Colonel dies in an explosion at a military golf course, the NCIS team must investigate a suspected terrorist attack with the help from the Army Criminal Investigative Division (CID). The CIA gives them a lead to an abandoned warehouse, but it turns out to be a trap---the warehouse is set to explode. McGee uses his computer skills to break into the secret government files to uncover the terrorist cell.

When the NCIS team learns that the missing 10 kilograms of highly toxic chemical weapons are now in the hands of Mamoun Sharif, a wanted terrorist, they will have to find a way to find the man and stop him before it's too late with the aid from Army Lt. Col. Hollis Mann and constant phone calls from Sharif himself.