While Liz and the Task Force track a notorious underground biohacker, Red initiates a strategy to extricate himself from a problematic position. Meanwhile, Cooper's integrity is tested with a difficult choice.

Liz and the Task Force investigate an infamous assassin who has a long history of weaponizing diseases, but has now turned to even more insidious activities. Meanwhile, Red and Dembe travel to Cuba in search of a lead, and Aram considers a new relationship. Elizabeth Bogush guest stars.