Gabriel and the Cybercom team head to Texas to help contain an outbreak of a deadly, rapidly spreading virus, but when Gabriel cyber-renders ground zero of the outbreak to isolate who Patient Zero might be, he and the team are shocked to see that the suspect is a criminal believed to have been executed a week earlier.

Gabriel and Riley must determine who is responsible for framing Gabriel when he is suspected of murder; Tetazoo leads a manhunt for Riley and Gabriel.

Riley and Gabriel are shocked when the identities of sleeper agents embedded in the U.S. government are revealed.