The death of an autistic youth in custody reveals a multitude of unusual and possibly illegal therapies being used, but also parents reluctant to pursue a prosecution.

The investigation into a prostitute's murder leads to a married plastic surgeon as the obvious suspect, but Kincaid has a hunch that an elaborate frame-up is in play.

A jogger killed in Central Park turns out to be the second wife of a former comedy club owner, who was acquitted of killing his first wife. And convicting him this time may hinge on tracing the path of a Columbian coin used as a subway token slug.

After an infant is found dead in his crib, it's determined he was poisoned, and all evidence points to the child's au pair.

Curtis, angered by the attitude of an old colleague of Briscoe's, looks beyond the findings of an IAB investigation and turns up evidence of police corruption that puts the DA's office into competition with an ambitious judge and Briscoe under investigation for stealing evidence from a police lockup.

The case against Huey Tate, a young man accused of shooting the well-known leader of the African-American Congress comes undone when the New York authorities learn that their chief witness was once an informant for the FBI, and is still under their protection.

A discrepancy concerning the time of death of a drive-by shooting victim leads McCoy and Ross to initiate prosecutions against both the shooter and the doctor who harvested her organs as transplant donations.

The murder of a bail bondsman looks fairly routine until the chance words of the chief suspect uncovers possible case-fixing between a shady lawyer and an unknown contact within the judicial system.

The murder of a corrections officer leads detectives to a women's prison where a guard was linked to an inmate Carmichael put away on drug charges and a confrontation with defense attorney Danielle Melnick.

Briscoe and Curtis reopen a case that was closed in the '60s when a vehicle is dredged from the Hudson River containing the remains of a murdered man.

The death of a corporate mogul caused by an overdose of a sexual performance-enhancing drug leads to a case with a witness that puts Curtis in a compromising position.

Jamie Ross returns as a defense attorney to represent a previous client who has key evidence concerning a prisoner on death row.

A taxi driver finds that his passenger is dead, leading the detectives to a case involving an insurance scam and Holocaust victims.

Under pressure from the department's top brass, a 20-year-old murder case, initally investigated by Briscoe's now retired boss, is reopened involving the slaying of a teen-age girl with the spoiled son of a politically connected family as the prime suspect.

The death of a cleric leads the detectives to a priest who was given information by a murder suspect outside of the church but insists that he can't discuss anything about it, bringing McCoy to question whether the confessional seal should apply.

The wife of an attorney with many disgruntled clients is killed but the detectives believe that he was the intended target as he was willing to reveal information despite confidentially agreements. As the investigation continues, his tumultuous love life is exposed and the prosecutors are suspicious of his desire to return to the courtroom.

A defense attorney who had just acquitted a cop killer is gunned down outside a Manhattan restaurant. The detectives start with police officers in the precinct of the injured officer, then to his brother, before they are led to a white supremacist who is part of a national network. McCoy is faced with the unlikely prospect that the defendant's attorney, his friend of 20 years and a friend of the slain lawyer, played a part in the murder of a Florida district attorney following the defendant's arrest. McCoy is able to make a deal that perserves the integrity of his adversary, but not without a cost.

A media-savvy attorney defends a black teenager accused of shooting an off-duty policy officer.

The investigation into the murder of a bounty hunter leads to a reporter with compromised ethics and a dubious defense strategy.

Briscoe bids farewell to the 27 as the prosecution of two women for killing each other's husbands comes to a successful conclusion.

An Iraqi immigrant who murders a former military policewoman in retaliation for torturing her brother at Abu Ghraib prison claims that she is covered as an enemy combatant under the terms of the Geneva Convention.

Fontana and Green are baffled by a series of flu-related deaths until they discover that the victims were given fake vaccine. McCoy goes after the con man who distributed the vaccine for murder.

After a man causes a massive train crash that results in multiple deaths, McCoy tries to prosecute him for murder despite his insanity defense. But McCoy finds himself hampered by a defense attorney whose own agenda may undercut that of his client.

A young girl is abducted in broad daylight, and the only link to the girl is an ex-convict who wants a deal before he's willing to talk.

The family of a man who once turned his customers into the police is slain, and the ensuing fracas pits McCoy against a corrupt D.E.A. agent.

The shooting of university student Jason Miles at a political rally hosted by controversial speaker Judith Barlow leaves any number of suspects, but after Green and Cassady prove that two of the people they've questioned are lying about their alibis, they turn their attention to Malcom Yates, a grad student who claimed to be with Jason's girlfriend at the time of his death. McCoy and Rubirosa realise that Yates went after Barlow because of her open criticism of stem-cell research, something that Yates had high hopes could help find a cure for his own Parkinsons.

When Nicole Bailey, the ex-wife of a respected former senator, is found murdered and brutalised in her home, Green and Cassady look first at the senator, but follow the trail of clues to a dysfunctional family with a number of potentially embarrassing secrets. McCoy finds himself in the hot seat when he is forced to argue the case in front of a judge more interested in public relations than justice.