Stardate: Unknown. Borrowing a captured Jem'Hadar attack ship, Sisko and crew embark on a mission to destroy the hidden base where all of the ketracel-white is stored for the entire Alpha Quadrant.

Stardate: 51145.3. After forming an attack plan on the Dominion, Sisko relinquishes command of the Defiant to Dax after accepting a promotion. On DS9, the resistance faces discovery when Odo links with another changeling.

Stardate: Unknown. Sisko mounts an attack to re-take DS9, while Rom faces charges as an enemy of the Dominion state.

Stardate: Unknown. When Sisko is picked to head up an attack on the Cardassian homeworld, the Prophets appear to him in a vision, warning him of impending doom if he leaves the station.

Stardate: Unknown. Sisko, laying low on Earth since the wormhole's disappearance, receives a vision of an unfamiliar woman he believes is the key to regaining contact with the Prophets. Meanwhile, Kira faces the challenge of commanding Deep Space Nine and upholding the fragile alliance with the Romulans, and Worf must cope with the loss of Jadzia Dax.

Stardate: 52152.6. Ezri Dax joins Sisko and his family on his quest for the Orb of the Emissary. Jadzia's friends and family seek a glorious battle that will earn her place in Sto-vo-kor. Kira gambles the alliance with Romulans by blockading their weapons installation on Bajor's moon.

Stardate: Unknown. Dr. Bashir is contacted again by Sloan of Section 31, who wants him to gather intel at an upcoming Romulan medical conference. Sisko agrees to send him, in order to learn more about Section 31 themselves.

Stardate: Unknown. The Prophets disapprove of Sisko’s upcoming marriage, and he must make hard choices about his priorities. Ezri and Worf are captured by Dominion forces. Gul Dukat, disguised as a Bajoran, infiltrates DS9 and becomes close to Kai Winn.

Stardate: Unknown. After the Breen attack Earth there are mixed emotions abound on DS9. Having revealed her secret regarding the Prophets to the disguised Dukat, Kai Winn turns her back on them, only to be convinced by Dukat to embrace the Pah Wraiths. On the home world of Cardassia, Legate Damar mounts a resistance to the Dominion.

Stardate: Unknown. Kira is sent to Cardassia to train their resistance. Dr. Bashir discovers that Odo has contracted the same disease threatening the Founders. Gowron arrives on DS9, announcing he’s taking control of the Klingon fleet from Martok.

Stardate: 52861.3. Odo begins his recovery from the deadly disease as Dr. Bashir informs him of Section 31's intentions of wiping out his race. A resistance mission goes bad for Kira and Garak and they end up hiding in the basement of the house that Garak grew up in, where they learned that Legate Damar has apparently become a casualty of war, despite him also hiding with them. Quark is chosen by the Grand Nagas as his successor upon his impending retirement to Risa.

Stardate: Unknown. Sisko leads, what he hopes will be, a final all-out assault on Cardassia Prime. Kira and Garak mount a suicidal assault on the Cardassian headquarters occupied by the Dominion, who in turn kill innocent women and children village by village in retaliation for the Resistance's attacks.

Stardate: Unknown. Sisko leads, what he hopes will be, a final all-out assault on Cardassia Prime. Kira and Garak mount a suicidal assault on the Cardassian headquarters occupied by the Dominion, who in turn kill innocent women and children village by village in retaliation for the Resistance's attacks.