The President has signed the New Powers Act in response to the Terrigen Fog creating new Inhumans and Truman Marsh is assigned to be the Avengers liaison to the government. Meanwhile, scientists backed by HYDRA enter a gamma storm with a stolen spaceship and are transformed into the U-Foes where they plan to take over HYDRA when Baron Strucker hasn't returned.

With the Avengers disbanded, a new team - the Mighty Avengers - steps in to take their place.