While searching for Jennifer Goines in post-WWI France, Cole and Jones encounter a dangerous group of time- travelers - the Guardians.

In 1953, Cole and Railly reunite with Agent Gale at the birth of the Army of the 12 Monkeys.

Cole and Railly find themselves at opposite ends of an unspeakable decision. Jones grows suspicious while Railly turns to an emotional ally for advice. All hell breaks loose during a massive fire-fight.