Cole and Railly have finally found peace living in the past. When a mysterious woman with apocalyptic visions of the future tells Cole it's not over, he must do the unthinkable to save the world... and the woman he loves.

The final conflict with the Army of the 12 Monkeys begins when the Witness returns to Project Splinter.

Jones sends Hannah back in time to 2007 on a personal mission that could be the key to everything.

The final battle against the Witness as the fate of time and mankind hangs in the balance. All the pieces finally come together to mark the end of the beginning.

When all hope is lost, Cole must complete his cycle so that his younger self will one day arrive at the end with the answer.