As Elizabeth prepares for the arrival of Iranian President Shiraz to sign a nuclear treaty, she uncovers a top secret plot to assassinate him on United States soil. At the same time, she must deal with a massive protest by the Human Rights Campaign in response to Iran’s plans to stone a gay citizen to death. Also, Elizabeth sees a therapist to deal with her PTSD.

When President Dalton gets word that the world’s most wanted terrorist, Jibral Disah, is hiding in Islamabad, he sends the “Murphy Station” – Henry, Jane and Jose – on a dangerous mission to eliminate the threat. Also, Elizabeth and Henry go to couples therapy.