After an Italian warship answers a distress call from a ship carrying Libyan refugees, Elizabeth is given 20 minutes to decide whether to question a passenger who claims to know the whereabouts of Jibral Disah, the most-wanted terrorist in the world. Also, Stevie brings her boyfriend Jareth home to meet her parents.

While Elizabeth accompanies Alison on a college campus tour, she is ambushed by protestors about a Chilean mining operation involving the U.S. and Chilean governments. Also, Henry, Jane and Jose Campos attempt to track down Jibral Disah's third wife, Hijriyyah

As Elizabeth holds peace talks between the prime ministers of India and Pakistan, a mysterious plane crash tied to both countries causes the three parties to reevaluate the deal. Also, in an attempt to help the NSA locate the terrorist Jibral Disah, Henry approaches a former teacher of one of Disah’s wives for information, and Elizabeth withstands a grueling interview with Jane Pauley.

Elizabeth learns that a member of the inner circle of the terrorist group Boko Haram has fallen ill with a deadly virus and, by leveraging his weakness, she formulates a plan to get them to release a group of schoolgirls they are holding captive. Also, Henry gets new information on the whereabouts of Jibral Disah that leads them closer to pinpointing his location.

After Elizabeth delivers her first speech to the United Nations General Assembly formally condemning the terrorist group Hizb-al Shahid, she discusses forming a coalition against them with the Russian Foreign Minister. However, the talks create a conflict of interest between Elizabeth and Henry, who is searching for a way to save Dmitri’s ill sister, Talia Petrov, from the Russian government.

When President Dalton gets word that the world’s most wanted terrorist, Jibral Disah, is hiding in Islamabad, he sends the “Murphy Station” – Henry, Jane and Jose – on a dangerous mission to eliminate the threat. Also, Elizabeth and Henry go to couples therapy.

When a storm destroys a naval base in Bahrain, Elizabeth urges President Dalton to reexamine his approach to climate change and his overall foreign policy, something that could jeopardize his re-election campaign. Also, the McCords worry that their family is being stalked when they discover Jason’s laptop may have been hacked.

With Algeria on the brink of a civil war, Elizabeth delicately negotiates a regime change, but her plans go awry when Roy Curtis, the trusted U.S. Ambassador to Algeria, dies unexpectedly. Also, Henry fights to save religious antiquities in Algeria when he discovers they are being destroyed by Hizb al-Shahid.

After U.S. environmental activists protesting China’s damage of a South China Sea reef are arrested for spying, Elizabeth finds herself in a stalemate with the Chinese foreign minister as she lobbies for their release.

After a bombing at a political rally in Angola, Elizabeth must find a way to respond to a “dissent memo” from the Bureau of African Affairs when they criticize the Dalton Administration’s lack of attention to the upcoming Angolan election.

When an imminent U.S.-France state dinner is jeopardized after a CIA operative is captured by French intelligence, Elizabeth must negotiate the operative’s release while keeping the event on track.