A Navy lieutenant on shore leave dies of the bubonic plague, sending the New Orleans team into a tailspin to locate all other sailers on liberty to control an outbreak and find the source. Special Agent Tony DiNozzo gives a helping hand.

An armored transport bus with Naval brig detainees on board crashes and four prisoners manage to escape.

It's revealed that a chief warrant officers' wife has been abducted, when his death is investigated. Fornell assists with the case.