As New Orleans grapples with the effects of COVID-19, Pride sends Tammy and Carter to investigate a suspicious death aboard a humanitarian ship offshore, where they learn that some crew members are infected with the deadly disease. Meanwhile, Wade is overwhelmed by the high volume in the morgue due to COVID-19.

As Tammy and Carter continue to investigate the suspicious death aboard a COVID-infected humanitarian ship offshore, Pride and the team discover that the PPE they were sent to distribute may hold the key to finding the killer.