Mona and Dee Dee attend Neil's wedding, where their conversation with the already-nervous bride in the bathroom leads her to call off the wedding. Mona believes they should stay out of the situation to avoid causing further harm; but Dee Dee insists on taking in the devastated Neil when he shows up on her doorstep. Spencer regrets giving an overly generous tip to the stripper at Neil's bachelor party, and tries to get the woman to return it. Meanwhile, Big Dee Dee fears that she and Phyllis may actually have things in common after they run into each other at a funeral and discover that they both dated the deceased.

After throwing together a baby shower for Neil and Janet, Dee Dee becomes concerned by the fact that she is the only person in attendance who is not attached. She begins to question her life and decision to pursue her career so aggressively. Meanwhile, Mona worries that her lack of maternal instinct could have a negative effect on her relationship with Chase. She tries spending time with Drew, and receives some advice from Big Dee Dee.