When the team is zapped into an alternate world where Penn is president, Sashi is a general, and Boone is a Supreme Court justice, Boone finds himself on the most popular game show in the galaxy where he must plead his case and compete against Rippen in an outrageous contest that will determine the fate of the Earth. However, Boone has a fear of public speaking.

Concerned about his abilities as a leader, Penn and his team are zapped into a world where they are sports balls to teach the other balls to defend themselves from their enemies.

Rippen falls for a space villain named Lady Starblaster.

Phil and Rippen tunnel into The Odyssey and damage the Multi Universe Transprojector, causing unbalance in the multiverse. Vortexes form in every world that Penn and his team have visited. Penn, Boone, and Sashi must travel to each world and close all of the vortexes before everything and everyone from all the worlds get sucked into nothingness. During their mission, Penn finds a crystal shard in the nothingness, which, according to Phyllis, is the key to finding his parents.

After a recap of the events of the first season. Penn, Sashi, and Boone are sent to a pirate world where whales act as the ships. Penn must get to a treasure before Rippen does, but finds himself teaming with a competitive female pirate in the process.

The trio find themselves in a fairy world in the midst of a wrestling tournament which Penn and Sashi must win to keep the forest out of evil hands. However, things are complicated by an argument between the two, forcing Boone to try to get them to mend their friendship.

Team Zero return to the Ball World to save its past from Rippen.

Penn's emotions cause problems for the latest mission.

Penn, Sashi, and Boone must travel to the three most dangerous places in the multiverse in order to free Penn's parents as Rippen plans to conquer the Most Dangerous World Imaginable with Larry and those with him after having to close its portal from the other side.