Jackson, Jamie and Agent Shaffer search for a chemist in Alabama who has evidence of Reiden Global's role in the growing animal problem. Meanwhile, Chloe, Mitch and Abraham fly to Rio de Janeiro to delay the local government's plan for a massive bat extermination and come up against a ruthless drug lord.

A tragedy strikes the team's only ally within the government, leaving Jackson and the team on their own to stop a surge of animal-related attacks from destroying the city of Geneva, Switzerland. Meanwhile, Dariela discovers something shocking about General Davies; and in the Canadian wilderness, Jamie comes across a troubling detail about Logan.