In Botswana, guides Jackson Oz and Abraham Kenyatta come across a mysterious series of lion attacks. In LA, two lions escape a zoo and go on a rampage, and investigative reporter Jamie Campbell believes that it's tied to pesticide infested food sold by Reiden Global.

Jackson discovers that Abraham is alive and stages a daring rescue to bring his friend home safely. Meanwhile, Jamie suspects that Reiden Global's pesticide is responsible for the lion attacks and convinces Mitch to help her. In Paris, a mysterious man approaches Chloe and asks her to accompany him.

Jackson and Abraham travel to Robert's isolated lab to recover his research. Meanwhile, Jamie convinces Mitch to go to New Orleans with her to approach a sympathetic senator, and Gaspald convinces Chloe to join forces with him.

The team travels to Portugal where they square off against a dangerous venom dealer in order to get one step closer to the cure. Also, Jackson's increasingly erratic behavior jeopardizes the entire team.

Mitch digs into Jackson’s past to get the answers they need to make the cure. Also, the rest of the team hunts for evidence related to the triple helix inside a quaint English town.

With Jackson missing, Mitch and Abraham race to find him before General Davies and the International Animal Defense Group can locate him and prevent the team from making a cure. Also, Jamie, Dariela and Allison make a last-ditch effort to convince the Russian government to drop out of the Noah Objective.

Mitch and Jamie brave an animal attack at the Russian Embassy in Washington, D.C., and Jackson finally gets the answers he’s been looking for from a surprising source.

Mitch and Jamie hatch a daring plan to undermine the Noah Objective once and for all, and the team reunites on the Island of Pangaea where the final pieces of the cure are put in place.

Mitch and Jamie hatch a daring plan to undermine the Noah Objective once and for all, and the team reunites on the Island of Pangaea where the final pieces of the cure are put in place.

Mitch seeks to rescue Clementine from her captors, and a glimpse into Jackson’s sister Abigail’s past reveals the origins of the hybrids.