Halstead relies on Marcel and Med's newly donated OR 2.0 to save his patient. Charles helps an elderly, confused patient who's mourning the loss of his high school sweetheart. As their wedding day approaches, Choi and April run into some roadblocks.

Charles and Cuevas help an elderly patient and her developmentally disabled grandson. Halstead treats a swimmer with a heart condition. Marcel considers using the OR 2.0 for surgery.

Marcel and Charles treat Lieu's gym buddy. Maggie and Halstead help a robbery-homicide suspect. Asher and Archer use Med's new opiate abuse AI program.