Tensions run high as hard truths ring out when Jeffrey, Danny, Camille, Maggie, Aaron, Arthur and Phillip are quarantined in an empty operating room after a possible exposure to Ebola; Jeffrey and Danny perform an emergency bypass after Arthur has a massive heart attack; Aaron and Camille reconcile.

Judge Aldrich's tenure as Alan's replacement is cut short by illness; Amy, an old friend of Danny's from medical school, joins the nursing staff and clashes with Camille over the care of a terminally ill patient; Kate and Billy hook up, but decide that they won't repeat the experience after they clash professionally during experimental laser surgery on an elderly cardiac patient; Amy rebuffs Danny's advances.