Riggs and Murtaugh team up again with Palmer, and together they gain inside knowledge of dangerous new cartel operations. As Riggs’ attachment to Palmer deepens, so do his impulsive actions, further worrying Avery and Delgado. Trish explores the potential of an amazing new career opportunity.

Murtaugh follows Riggs down to Mexico, where he plans to avenge his wife's death and finish off Tito Flores once and for all. Once back in the States, they have a few people to answer to during the ongoing investigation around Flores, including Murtaugh's family. Avery is questioned by Internal Affairs about the integrity of his department.