A doctor is found dead in the pool of a wellness clinic. Riggs suspects a drug angle and asks Agent Palmer for help.

After a mansion break-in turns into a homicide, Murtaugh and Riggs set out to find the culprit. Murtaugh and Trish question their trust in Riana as she gets into some trouble with new friends. Riggs recalls his troubling childhood and finds a true family with Molly and Ben.