MacGyver and Jack search for Riley, using a microwave and a power strip, after she mysteriously disappears and hacks into the NSA, possibly unleashing World War III. Also, Bozer goes on his first official mission, and Jack opens up about his history with Riley’s mother, Diane.

When Matty’s goddaughter and her boyfriend are killed in a San Francisco park, Mac and the team investigate the crime and start to suspect that the 1970s Zodiac Killer has returned.

Murdoc moves forward with his plans for revenge against MacGyver by recruiting his recently released former cellmate to infiltrate the Phoenix Complex as a “lab technician” and kill every agent inside.

Using a cell phone and soccer ball, MacGyver and the team search for a Navy SEAL who is believed to be alive in captivity in the Middle East.

Using a cassette player and a plastic bucket, Mac and the team attempt to extinguish a massive oil wellhead fire in a Nigerian village, set by a rebel group, which is trying to topple its government by destroying their most valuable resource.

After one of Murdoc's go-to assassins agrees to hand over Murdoc to MacGyver in exchange for $10 million, the team finds itself protecting Murdoc from his former mentor, Nicholas Helman, who wants him dead. Also, Jack realizes he may still have feelings for Riley's mother, Diane.

MacGyver gets a shocking surprise when he tries to tell Matty that he’s quitting the Phoenix Foundation.

Three months after quitting the Phoenix Foundation and moving to Nigeria, Mac puts aside his differences with his father and returns when he hears Jack is the target of a murderous dictator he double-crossed.

Murdoc abducts MacGyver’s girlfriend, Nasha, to force Mac to help him rescue his son, Cassian, from a kidnapper. Also, a dangerous individual from Murdoc’s personal life shows up, giving Mac a glimpse into the villain’s past.

The Phoenix must recover the body of a pilot whose plane crashed while testing an experimental laser mapping system that MacGyver designed. Also, Riley tries to identify the hacker who tricked a SWAT team into arresting her and Elwood.

Matty’s ex-husband, Ethan, asks her for help when a criminal organization, S-Company, kidnaps his wife and daughter, forcing Matty to decide if she’s willing to commit treason in order to help him save his family. Also, Riley joins Billy Colton and Mama Colton on a mission to Paris and makes a heartbreaking discovery.