MacGyver and Jack search for Riley, using a microwave and a power strip, after she mysteriously disappears and hacks into the NSA, possibly unleashing World War III. Also, Bozer goes on his first official mission, and Jack opens up about his history with Riley’s mother, Diane.

After one of Murdoc's go-to assassins agrees to hand over Murdoc to MacGyver in exchange for $10 million, the team finds itself protecting Murdoc from his former mentor, Nicholas Helman, who wants him dead. Also, Jack realizes he may still have feelings for Riley's mother, Diane.