Tick and Arthur pursue the trail of the bank robbers into the gambling underworld. Overkill reconnects with an old mentor and learns his enemy The Duke may still be alive.

A strange bit of information sends Dangerboat in to lockdown. Dot frees Overkill of a burden and joins him on a mission. Meanwhile, Superian takes Arthur's advice - badly.

Tick and Arthur fight a beaurocratic battle to save an innocent creature from AEGIS experimentation. Dot tours an AEGIS open house, as Overkill visits an old friend.

Tick and Arthur must take care of six adorable babies while hiding them from AEGIS. Joan and Kevin lend a hand. Superian unexpectedly drops in for a therapy session.

Tick and Arthur join the Flag-5 and undergo initiation with their fellow team members. Walter and Dot throw a wrench into Arthur's dream come true. The Duke makes a deadly move on AEGIS.

The Tick, Arthur, Dot, and the rest of the family must battle The Duke and AEGIS itself. Miss Lint reveals her true goal and Superian weighs the pros and cons of accidental genocide.